Výzkumné instituce sdružené v NÚVR se mj. zavázaly k tomu, že vytvoří více než 600 klasifikovatelných výstupů, z toho přes 400 odborných publikací. Zde najdete přehled prací zveřejněných v odborných časopisech spadajících do prvního kvartilu daného oboru a některé další výstupy projektu.
Investigation of the potential effects of estrogen receptor modulators on immune checkpoint molecules. Abramenko, Nikita, Fréderic Vellieux, Kateřina Veselá, Zdeněk Kejík, Jan Hajduch, Michal Masařík, Petr Babula, David Hoskovec, Karel Pacák, Pavel Martásek, Karel Smetana a Milan Jakubek. Scientific Reports [online], 2024, 14(1), 3043.
doi: 10.1038/s41598-024-51804-2
Mechanism of BCDX2-mediated RAD51 nucleation on short ssDNA stretches and fork DNA. Akita, Masaki, Paul Girvan, Mario Spirek, Jiri Novacek, David Rueda, Zbynek Prokop A Lumir Krejci. Nucleic Acids Research [online], 2024, 52(19), 11738–11752.
doi: 10.1093/nar/gkae770
Topological stress triggers persistent DNA lesions in ribosomal DNA with ensuing formation of PML-nucleolar compartment. Alexandra Urbancokova, Terezie Hornofova, Josef Novak, Sarka Andrs Salajkova, Sona Stemberkova Hubackova, Alena Uvizl, Tereza Buchtova Martin Mistrik, Brian McStay, Zdenek Hodny, Jiri Bartek a Pavla Vasicova. Elife, 2024 Oct 10:12:RP91304.
doi: 10.7554/eLife.91304.3.sa0
Chemical modification of bradykinin-polymer conjugates for optimum delivery of nanomedicines to tumors. Appiah, Enoch, Hideaki Nakamura, Anthony Assumang, Tomáš Etrych a Mamoru Haratake. Nanomedicine: Nanotechnology, Biology and Medicine [online], 2024, 57, 102744.
doi: 10.1016/j.nano.2024.102744
FAM110A promotes mitotic spindle formation by linking microtubules with actin cytoskeleton. Aquino-Perez, Cecilia, Mahira Safaralizade, Roman Podhajecky, Hong Wang, Zdenek Lansky, Robert Grosse A Libor Macurek. Proceedings of the National Academy of Sciences [online], 2024, 121(29), e2321647121.
Extensive targeting of chemical space at the prime side of ketoamide inhibitors of rhomboid proteases by branched substituents empowers their selectivity and potency. Bach, Kathrin, Jan Dohnálek, Jana Škerlová, Ján Kuzmík, Edita Poláchová, Stancho Stanchev, Pavel Majer, Jindřich Fanfrlík, Adam Pecina, Jan Řezáč, Martin Lepšík, Valentin Borshchevskiy, Vitaly Polovinkin A Kvido Strisovsky. European Journal of Medicinal Chemistry [online], 2024, 275, 116606.
doi: 10.1016/j.ejmech.2024.116606
Advanced technologies towards improved HPV diagnostics. Bartosik, Martin, Ludmila Moranova, Nasim Izadi, Johana Strmiskova, Ravery Sebuyoya, Jitka Holcakova a Roman Hrstka. Journal of Medical Virology [online], 2024, 96(2), e29409.
doi: 10.1002/jmv.29409
HIV-protease inhibitors potentiate the activity of carfilzomib in triple-negative breast cancer. Besse, Andrej, Lenka Sedlarikova, Lorina Buechler, Marianne Kraus, Chieh-Hsiang Yang, Nicol Strakova, Karel Soucek, Jiri Navratil, Marek Svoboda, Alana L. Welm, Markus Joerger, Christoph Driessen a Lenka Besse. British Journal of Cancer [online], 2024, 131(5), 918–930.
doi: 10.1038/s41416-024-02774-9
Impact of PIK3CA gain and PTEN loss on mantle cell lymphoma biology and sensitivity to targeted therapies. Bettazova, Nardjas, Jana Senavova, Kristyna Kupcova, Dana Sovilj, Anezka Rajmonova, Ladislav Andera, Karla Svobodova, Adela Berkova, Zuzana Zemanova, Lenka Daumova, Vaclav Herman, Alexandra Dolníkova, R. Eric Davis, Marek Trneny, Pavel Klener a Ondrej Havranek. Blood Advances [online], 2024, 8(20), 5279–5289.
doi: 10.1182/bloodadvances.2024013205
CD20 expression regulates CD37 levels in B-cell lymphoma – implications for immunotherapies. Bobrowicz, Malgorzata, Aleksandra Kusowska, Marta Krawczyk, Andriy Zhylko, Christopher Forcados, Aleksander Slusarczyk, Joanna Barankiewicz, Joanna Domagala, Matylda Kubacz, Michal Šmída, Lenka Dostalova, Katsiaryna Marhelava, Klaudyna Fidyt, Monika Pepek, Iwona Baranowska, Anna Szumera-Cieckiewicz, Else Marit Inderberg, Sébastien Wälchli, Monika Granica, Agnieszka Graczyk-Jarzynka, Martyna Majchrzak, Marcin Poreba, Carina Lynn Gehlert, Matthias Peipp, Malgorzata Firczuk, Monika Prochorec-Sobieszek a Magdalena Winiarska. OncoImmunology [online], 2024, 13(1), 2362454.
doi: 10.1080/2162402X.2024.2362454
In vivo interaction screening reveals liver-derived constraints to metastasis. Borrelli, Costanza, Morgan Roberts, Davide Eletto, Marie-Didiée Hussherr, Hassan Fazilaty, Tomas Valenta, Atefeh Lafzi, Jonas A. Kretz, Elena Guido Vinzoni, Andromachi Karakatsani, Srivathsan Adivarahan, Ardian Mannhart, Shoichiro Kimura, Ab Meijs, Farah Baccouche Mhamedi, Ilhan E. Acar, Kristina Handler, Xenia Ficht, Randall J. Platt, Salvatore Piscuoglio a Andreas E. Moor. Nature [online], 2024, 632(8024), 411–418.
doi: 10.1038/s41586-024-07715-3
Iron chelators as mitophagy agents: Potential and limitations. Brogyanyi, Tereza, Zdeněk Kejík, Kateřina Veselá, Petr Dytrych, David Hoskovec, Michal Masařik, Petr Babula, Robert Kaplánek, Tomáš Přibyl, Jaroslav Zelenka, Tomáš Ruml, Martin Vokurka, Pavel Martásek a Milan Jakubek. Biomedicine & Pharmacotherapy [online], 2024, 179, 117407.
doi: 10.1016/j.biopha.2024.117407
Imatinib therapy of chronic myeloid leukemia significantly reduces carnitine cell intake, resulting in adverse events. Burda, Pavel, Alzbeta Hlavackova, Vendula Polivkova, Nikola Curik, Adam Laznicka, Jitka Krizkova, Jiri Suttnar, Pavel Klener a Katerina Machova Polakova. Molecular Metabolism [online], 2024, 88, 102016.
doi: 10.1016/j.molmet.2024.102016
Sensitive quantification of fibroblast activation protein and high-throughput screening for inhibition by FDA-approved compounds. Čermáková, Kateřina, Adéla Šimková, Filip Wichterle, Robin Kryštůfek, Jana Staňurová, Zdislava Vaníčková, Petr Bušek, Jan Konvalinka a Pavel Šácha. European Journal of Medicinal Chemistry [online], 2024, 280, 116948.
doi: 10.1016/j.ejmech.2024.116948
Antineoplastics for treating Alzheimer’s disease and dementia: Evidence from preclinical and observational studies. Das, Viswanath, John H. Miller, Charanraj Goud Alladi, Narendran Annadurai, Juan Bautista De Sanctis, Lenka Hrubá a Marián Hajdúch. Medicinal Research Reviews [online], 2024, 44(5), 2078–2111.
doi: 10.1002/med.22033
DEB, Rahul, Marcelo D. T. TORRES, Miroslav BOUDNÝ, Markéta KOBĚRSKÁ, Floriana CAPPIELLO, Miroslav POPPER, Kateřina DVOŘÁKOVÁ BENDOVÁ, Martina DRABINOVÁ, Adelheid HANÁČKOVÁ, Katy JEANNOT, Computational Design of Pore-Forming Peptides with Potent Antimicrobial and Anticancer Activities. Miloš Petřík, Maria Luisa Mangoni, Gabriela Balíková Novotná, Marek Mráz, Cesar De La Fuente-Nunez a Robert Vácha. Journal of Medicinal Chemistry [online], 2024, 67(16), 14040–14061.
doi: 10.1021/acs.jmedchem.4c00912
New Inhibitors of Bcr-Abl Based on 2,6,9-Trisubstituted Purine Scaffold Elicit Cytotoxicity in Chronic Myeloid Leukemia-Derived Cell Lines Sensitive and Resistant to TKIs. Delgado, Thalia, Denisa Veselá, Hana Dostálová, Vladimír Kryštof, Veronika Vojáčková, Radek Jorda, Alejandro Castro, Jeanluc Bertrand, Gildardo Rivera, Mario Faúndez, Miroslav Strnad, Christian Espinosa-Bustos a Cristian O. Salas. Pharmaceutics [online], 2024, 16(5), 649.
doi: 10.3390/pharmaceutics16050649
Simultaneous deletion of ORMDL1 and ORMDL3 proteins disrupts immune cell homeostasis. Demkova, Livia, Viktor Bugajev, Miroslava K. Adamcova, Ladislav Kuchar, Srdjan Grusanovic, Meritxell Alberich-Jorda, Petr Draber A Ivana Halova. Frontiers in Immunology [online], 2024, 15, 1376629.
doi: 10.3389/fimmu.2024.1376629
Blockage of BCL-XL overcomes venetoclax resistance across BCL2+ lymphoid malignancies irrespective of BIM status. Dolnikova, Alexandra, Dmitry Kazantsev, Magdalena Klanova, Eva Pokorna, Dana Sovilj, Cristina Daniela Kelemen, Liliana Tuskova, Eva Hoferkova, Marek Mraz, Karel Helman, Nikola Curik, Katerina Machova Polakova, Ladislav Andera, Marek Trneny a Pavel Klener. Blood Advances [online], 2024, 8(13), 3532–3543.
doi: 10.1182/bloodadvances.2024012906
Pre-existing cell subpopulations in primary prostate cancer tumors display surface fingerprints of docetaxel-resistant cells. Drápela, Stanislav, Barbora Kvokačková, Eva Slabáková, Anna Kotrbová, Kristína Gömöryová, Radek Fedr, Daniela Kurfürstová, Martin Eliáš, Vladimír Študent Jr, Frederika Lenčéšová, Ganji Sri Ranjani, Vendula Pospíchalová, Vítězslav Bryja, Wytske M. Van Weerden, Martin Puhr, Zoran Culig, Jan Bouchal a Karel Souček. Cellular Oncology [online], 2024, 48(1), 205–218.
doi: 10.1007/s13402-024-00982-2
Health-related quality of life and symptoms of chronic myeloid leukemia patients after discontinuation of tyrosine kinase inhibitors: results from the EURO-SKI Trial. Efficace, Fabio, Francois-Xavier Mahon, Johan Richter, Alfonso Piciocchi, Marta Cipriani, Franck E. Nicolini, Jiri Mayer, Daniela Zackova, Jeroen J. W. M. Janssen, Panayiotis Panayiotidis, Hanne Vestergaard, Perttu Koskenvesa, Antonio Almeida, Henrik Hjorth-Hansen, Joaquin Martinez-Lopez, Ulla Olsson-Strömberg, Andreas Hochhaus, Marc G. Berger, Gabriel Etienne, Hana Klamova, Edgar Faber, Philippe Rousselot, Markus Pfirrmann a Susanne Saussele. Leukemia [online], 2024, 38(8), 1722–1730.
doi: 10.1038/s41375-024-02341-4
Solid-Phase Synthesis as a Tool to Create Exactly Defined, Branched Polymer Vectors for Cell Membrane Targeting. Elter, Johanna K., Veronika Liščáková, Oliver Moravec, Martina Vragović, Marcela Filipová, Petr Štěpánek, Pavel Šácha a Martin Hrubý. Macromolecules [online], 2024, 57(3), 1050–1071.
doi: 10.1021/acs.macromol.3c02600
Metaproteomic analysis from cervical biopsies and cytologies identifies proteinaceous biomarkers representing both human and microbial species. Faktor, Jakub, Tomas Henek, Lenka Hernychova, Ashita Singh, Borek Vojtesek, Joanna Polom, Ramya Bhatia, Karol Polom, Kate Cuschieri, Margaret Cruickshank, Mahalakshmi Gurumurthy, David R. Goodlett, Sofian Al Shboul, Shailesh Kumar Samal, Ted Hupp, Emmanouil Kalampokas a Sachin Kote. Talanta [online], 2024, 278, 126460.
doi: 10.1016/j.talanta.2024.126460
Second bone marrow transplantation into regenerating hematopoiesis enhances reconstitution of immune system. Faltusová, Kateřina, Martin Báječný, Tomáš Heizer, Petr Páral, Chia-Ling Chen, Katarína Szikszai, Pavel Klener a Emanuel Nečas. Frontiers in Immunology [online], 2024, 15, 1405210.
doi: 10.3389/fimmu.2024.1405210
Structural optimization of diblock polymers that undergo thermo-responsive nanoparticle self-assembly for intravitreal drug delivery. Fergie, Kyle J., David R. Wilson, Lucie Kracíková, Ladislav Androvič, Hannah Yamagata, Ellen B. Wang, Hojin Yoon, Geoffrey M. Lynn a Richard Laga. European Polymer Journal [online], 2024, 212, 113054.
doi: 10.1016/j.eurpolymj.2024.113054
Inflammation, Autoimmunity and Neurodegenerative Diseases,Therapeutics and Beyond. Garmendia, Jenny Valentina, Claudia Valentina De Sanctis, Viswanath Das, Narendran Annadurai, Marián Hajduch a Juan Bautista De Sanctis. Current Neuropharmacology [online], 2024, 22(6), 1080–1109.
doi: 10.2174/1570159X22666231017141636
Novel strategies for enhanced fluorescence visualization of glioblastoma tumors based on HPMA copolymers conjugated with tumor targeting and/or cell‐penetrating peptides. Grosmanová, Eliška, Robert Pola, Marcela Filipová, Maxime Henry, Jean‐Luc Coll a Tomáš Etrych. VIEW [online], 2024, 5(3), 20230116.
doi: 10.1002/VIW.20230116
Small protein blockers of human IL-6 receptor alpha inhibit proliferation and migration of cancer cells. Groza, Yaroslava, Lukáš Lacina, Milan Kuchař, Leona Rašková Kafková, Kateřina Zachová, Olga Janoušková, Radim Osička, Jiří Černý, Hana Petroková, Joanna Maria Mierzwicka, Natalya Panova, Petr Kosztyu, Kristýna Sloupenská, Jan Malý, Jozef Škarda, Milan Raška, Karel Smetana a Petr Malý. Cell Communication and Signaling [online], 2024, 22(1), 261.
doi: 10.1186/s12964-024-01630-w
Polymer-Tethered Quenched Fluorescent Probes for Enhanced Imaging of Tumor-Associated Proteases. Hadzima, Martin, Franco F. Faucher, Kristýna Blažková, Joshua J. Yim, Matteo Guerra, Shiyu Chen, Emily C. Woods, Ki Wan Park, Pavel Šácha, Vladimír Šubr, Libor Kostka, Tomáš Etrych, Pavel Majer, Jan Konvalinka a Matthew Bogyo. ACS Sensors [online], 2024, 9(7), 3720–3729.
doi: 10.1021/acssensors.4c00912
The non-canonical BAF chromatin remodeling complex is a novel target of spliceosome dysregulation in SF3B1-mutated chronic lymphocytic leukemia. Hägerstrand, Daniel, Blaž Oder, Diego Cortese, Ying Qu, Amrei Binzer-Panchal, Cecilia Österholm, Teresa Del Peso Santos, Leily Rabbani, Hassan Foroughi Asl, Aron Skaftason, Viktor Ljungström, August Lundholm, Maria Koutroumani, Zahra Haider, Cecilia Jylhä, John Mollstedt, Larry Mansouri, Karla Plevova, Andreas Agathangelidis, Lydia Scarfò, Marine Armand, Alice F. Muggen, Neil E. Kay, Tait Shanafelt, Davide Rossi, Lukas M. Orre, Sarka Pospisilova, Konstantin Barylyuk, Frederic Davi, Mattias Vesterlund, Anton W. Langerak, Janne Lehtiö, Paolo Ghia, Kostas Stamatopoulos, Lesley-Ann Sutton a Richard Rosenquist. Leukemia [online], 2024, 38(11), 2429–2442.
doi: 10.1038/s41375-024-02379-4
Ferrocene- and ruthenium arene-containing glycomimetics as selective inhibitors of human galectin-1 and -3. Hamala, Vojtěch, Martin Kurfiřt, Lucie Červenková Šťastná, Hedvika Hujerová, Jana Bernášková, Kamil Parkan, Jakub Kaminský, Nina Habanová, Jaroslav Kozák, Alžběta Magdolenová, Martin Zavřel, Tatiana Staroňová, Veronika Ostatná, Lucie Žaloudková, Aleš Daňhel, Jitka Holčáková, Petr Voňka, Roman Hrstka a Jindřich Karban. Inorganic Chemistry Frontiers [online], 2024, 11(21), 7588–7609.
doi: 10.1039/D4QI01555J
Improving the anticancer activity of fluorinated glucosamine and galactosamine analogs by attachment of a ferrocene or ruthenium tetrazene motif. Hamala, Vojtěch, Kateřina Ondrášková, Lucie Červenková Šťastná, Aleš Krčil, Monika Müllerová, Martin Kurfiřt, Kateřina Hiršová, Jitka Holčáková, Róbert Gyepes, Ivana Císařová, Jana Bernášková, Roman Hrstka a Jindřich Karban. Applied Organometallic Chemistry [online], 2024, 38(5), e7399.
doi: 10.1002/aoc.7399
Protein cargo in extracellular vesicles as the key mediator in the progression of cancer. Hánělová, Klára, Martina Raudenská, Michal Masařík a Jan Balvan. Cell Communication and Signaling [online], 2024, 22(1), 25.
doi: 10.1186/s12964-023-01408-6
Survival in Elderly Ovarian Cancer Remains Challenging in the Nordic Countries. Hemminki, Kari, Frantisek Zitricky, Asta Försti a Akseli Hemminki. Cancers [online], 2024, 16(12), 2198.
Complex Relationships between Diagnostics and Survival in Chronic Lymphocytic Leukemia in Denmark, Finland, Norway, and Sweden. Hemminki, Kari, Frantisek Zitricky, Asta Försti, Tuija Tapaninen, Akseli Hemminki, Gunnar Juliusson a Carsten Utoft Niemann. Cancers [online], 2024, 16(18), 3229.
Rewired glutamate metabolism diminishes cytostatic action of L-asparaginase. Hlozkova, Katerina, Maryna Vasylkivska, Adam Boufersaoui, Bryan Marzullo, Matus Kolarik, Natividad Alquezar-Artieda, Mehak Shaikh, Nadia Fatemeh Alaei, Marketa Zaliova, Martina Zwyrtkova, Violeta Bakardijeva-Mihaylova, Meritxell Alberich-Jorda, Jan Trka, Daniel A. Tennant a Julia Starkova. Cancer Letters [online], 2024, 605, 217242.
doi: 10.1016/j.canlet.2024.217242
Nuclear patterns of phosphatidylinositol 4,5‐ and 3,4‐bisphosphate revealed by super‐resolution microscopy differ between the consecutive stages of RNA polymerase II transcription. Hoboth, Peter, Martin Sztacho a Pavel Hozák. The FEBS Journal [online], 2024, 291(19), 4240–4264.
doi: 10.1111/febs.17136
Stromal cells engineered to express T cell factors induce robust CLL cell proliferation in vitro and in PDX co-transplantations allowing the identification of RAF inhibitors as anti-proliferative drugs. Hoferkova, Eva, Vaclav Seda, Sona Kadakova, Jan Verner, Tomas Loja, Kvetoslava Matulova, Hana Skuhrova Francova, Eva Ondrouskova, Daniel Filip, Nicolas Blavet, Miroslav Boudny, Gabriela Mladonicka Pavlasova, Josef Vecera, Laura Ondrisova, Petra Pavelkova, Krystof Hlavac, Lenka Kostalova, Androniki Michaelou, Sarka Pospisilova, Jana Dorazilova, Vaclav Chochola, Josef Jaros, Michael Doubek, Marie Jarosova, Ales Hampl, Lucy Vojtova, Leos Kren, Jiri Mayer a Marek Mraz. Leukemia [online], 2024, 38(8), 1699–1711.
doi: 10.1038/s41375-024-02284-w
A comprehensive analysis of germline predisposition to early-onset ovarian cancer. Horackova, Klara, Petra Zemankova, Petr Nehasil, Michal Vocka, Milena Hovhannisyan, Katerina Matejkova, Marketa Janatova, Marta Cerna, Petra Kleiblova, Sandra Jelinkova, Barbora Stastna, Pavel Just, Tatana Dolezalova, Barbora Nemcova, Marketa Urbanova, Monika Koudova, Jana Hazova, Eva Machackova, Lenka Foretova, Viktor Stranecky, Michal Zikan, Zdenek Kleibl a Jana Soukupova. Scientific Reports [online], 2024, 14(1), 16183.
doi: 10.1038/s41598-024-66324-2
Population‐specific validation and comparison of the performance of 77‐ and 313‐variant polygenic risk scores for breast cancer risk prediction. Hovhannisyan, Milena, Petra Zemankova, Petr Nehasil, Katerina Matejkova, Marianna Borecka, Marta Cerna, Tatana Dolezalova, Lenka Dvorakova, Lenka Foretova, Klara Horackova, Sandra Jelinkova, Pavel Just, Marta Kalousova, Jan Kral, Eva Machackova, Barbora Nemcova, Marketa Safarikova, Drahomira Springer, Barbora Stastna, Spiros Tavandzis, Michal Vocka, Tomas Zima, Jana Soukupova, Petra Kleiblova, Corinna Ernst, Zdenek Kleibl a Marketa Janatova. Cancer [online], 2024, 130(17), 2978–2987.
doi: 10.1002/cncr.35337
Distinct pattern of genomic breakpoints in CML and BCR::ABL1-positive ALL: analysis of 971 patients. Hovorkova, Lenka, Lucie Winkowska, Justina Skorepova, Manuela Krumbholz, Adela Benesova, Vaclava Polivkova, Julia Alten, Michela Bardini, Claus Meyer, Rathana Kim, Toby N. Trahair, Emmanuelle Clappier, Sabina Chiaretti, Michelle Henderson, Rosemary Sutton, Lucie Sramkova, Jan Stary, Katerina Machova Polakova, Rolf Marschalek, Markus Metzler, Giovanni Cazzaniga, Gunnar Cario, Jan Trka, Marketa Zaliova a Jan Zuna. Molecular Cancer [online], 2024, 23(1), 138.
doi: 10.1186/s12943-024-02053-4
Therapeutic strategies and treatment sequencing in patients with chronic lymphocytic leukemia: An international study of ERIC, the European Research Initiative on CLL. Chatzikonstantinou, Thomas, Lydia Scarfò, Eva Minga, Georgios Karakatsoulis, Dimitra Chamou, Jana Kotaskova, Gloria Iacoboni, Christos Demosthenous, Elisa Albi, Miguel Alcoceba, Salem Al‐Shemari, Thérèse Aurran‐Schleinitz, Francesca Bacchiarri, Sofia Chatzileontiadou, Rosa Collado, Zadie Davis, Marcos Daniel De Deus Santos, Maria Dimou, Elena Dmitrieva, David Donaldson, Gimena Dos Santos, Barbara Dreta, Maria Efstathopoulou, Shaimaa El‐Ashwah, Alicia Enrico, Andrzej Frygier, Sara Galimberti, Andrea Galitzia, Eva Gimeno, Valerio Guarente, Romain Guieze, Sean Harrop, Eleftheria Hatzimichael, Yair Herishanu, José‐Ángel Hernández‐Rivas, Ozren Jaksic, Elżbieta Kalicińska, Kamel Laribi, Volkan Karakus, Arnon P. Kater, Bonnie Kho, Maria Kislova, Εliana Konstantinou, Maya Koren‐Michowitz, Ioannis Kotsianidis, Zuzana Kubova, Jorge Labrador, Deepesh Lad, Luca Laurenti, Thomas Longval, Alberto Lopez‐Garcia, Juan Marquet, Stanislava Maslejova, Carlota Mayor‐Bastida, Biljana Mihaljevic, Ivana Milosevic, Fatima Miras, Riccardo Moia, Marta Morawska, Uttam K. Nath, Almudena Navarro‐Bailón, Jacopo Olivieri, Irina Panovska‐Stavridis, Maria Papaioannou, Cheyenne Pierie, Anna Puiggros, Gianluigi Reda, Gian M. Rigolin, Rosa Ruchlemer, Mattia Schipani, Annett Schiwitza, Yandong Shen, Tereza Shokralla, Martin Simkovic, Svetlana Smirnova, Dina S. A. Soliman, Stephan Stilgenbauer, Tamar Tadmor, Kristina Tomic, Eric Tse, Theodoros Vassilakopoulos, Andrea Visentin, Candida Vitale, George Vrachiolias, Vojin Vukovic, Renata Walewska, Zhenshu Xu, Munci Yagci, Lucrecia Yañez, Mohamed Yassin, Jana Zuchnicka, David Oscier, Alessandro Gozzetti, Panagiotis Panagiotidis, Francesc Bosch, Paolo Sportoletti, Blanca Espinet, Gerassimos A. Pangalis, Viola M. Popov, Stephen Mulligan, Maria Angelopoulou, Fatih Demirkan, Tomas Papajík, Bella Biderman, Roberta Murru, Marta Coscia, Constantine Tam, Antonio Cuneo, Gianluca Gaidano, Rainer Claus, Niki Stavroyianni, Livio Trentin, Darko Antic, Lukas Smolej, Olga B. Kalashnikova, Mark Catherwood, Martin Spacek, Sarka Pospisilova, Michael Doubek, Eugene Nikitin, Anastasia Chatzidimitriou, Paolo Ghia a Kostas Stamatopoulos. HemaSphere [online], 2024, 8(9), e70004.
doi: 10.1002/hem3.70004
LAMP‐based electrochemical platform for monitoring HPV genome integration at the mRNA level associated with higher risk of cervical cancer progression. Izadi, Nasim, Johana Strmiskova, Milan Anton, Jitka Hausnerova a Martin Bartosik. Journal of Medical Virology [online], 2024, 96(10), e70008.
doi: 10.1002/jmv.70008
NDRG1 acts as an oncogene in triple-negative breast cancer and its loss sensitizes cells to mitochondrial iron chelation. Jadhav, Sukanya B., Michaela Vondrackova, Petra Potomova, Cristian Sandoval-Acuña, Jana Smigova, Kristyna Klanicova, Daniel Rosel, Jan Brabek, Jan Stursa, Lukas Werner a Jaroslav Truksa. Frontiers in Pharmacology [online], 2024, 15, 1422369.
doi: 10.3389/fphar.2024.1422369
Attenuated cell cycle and DNA damage response transcriptome signatures and overrepresented cell adhesion processes imply accelerated progression in patients with lower‐risk myelodysplastic neoplasms. Kaisrlikova, Monika, David Kundrat, Pavla Koralkova, Iva Trsova, Zuzana Lenertova, Hana Votavova, Michaela Dostalova Merkerova, Zdenek Krejcik, Jitka Vesela, Martin Vostry, Radka Simeckova, Marketa Stastna Markova, Marie Lauermannova, Anna Jonasova, Jaroslav Cermak, Vladimir Divoky a Monika Belickova. International Journal of Cancer [online], 2024, 154(9), 1652–1668.
doi: 10.1002/ijc.34834
Molecular Screening in Anaplastic Lymphoma Kinase–Positive Anaplastic Large Cell Lymphoma: Anaplastic Lymphoma Kinase Analysis, Next-Generation Sequencing Fusion Gene Detection, and T-Cell Receptor Immunoprofiling. Kalinova, Marketa, Marcela Mrhalova, Edita Kabickova, Michael Svaton, Aneta Skotnicova, Zuzana Prouzova, Zdenka Krenova, Alexandra Kolenova, Martina Divoka, Eva Fronkova a Roman Kodet. Modern Pathology [online], 2024, 37(3), 100428.
doi: 10.1016/j.modpat.2024.100428
Tertiary lymphoid structures and B cells determine clinically relevant T cell phenotypes in ovarian cancer. Kasikova, Lenka, Jana Rakova, Michal Hensler, Tereza Lanickova, Jana Tomankova, Josef Pasulka, Jana Drozenova, Katerina Mojzisova, Anna Fialova, Sarka Vosahlikova, Jan Laco, Ales Ryska, Pavel Dundr, Roman Kocian, Tomas Brtnicky, Petr Skapa, Linda Capkova, Marek Kovar, Jan Prochazka, Ivan Praznovec, Vladimir Koblizek, Alice Taskova, Hisashi Tanaka, Robert Lischke, Fernando Casas Mendez, Jiri Vachtenheim, Viola Heinzelmann-Schwarz, Francis Jacob, Iain A. Mcneish, Michal J. Halaska, Lukas Rob, David Cibula, Sandra Orsulic, Lorenzo Galluzzi, Radek Spisek a Jitka Fucikova. Nature Communications [online], 2024, 15(1), 2528.
doi: 10.1038/s41467-024-46873-w
Novel triterpenoid pyrones, phthalimides and phthalates are selectively cytotoxic in CCRF-CEM cancer cells – Synthesis, potency, and mitochondrial mechanism of action. Kazakova, Anna, Ivo Frydrych, Nikola Jakubcová, Jan Pokorný, Barbora Lišková, Soňa Gurská, Petr Džubák, Marián Hajdúch a Milan Urban. European Journal of Medicinal Chemistry [online], 2024, 269, 116336.
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Cyanine dyes in the mitochondria-targeting photodynamic and photothermal therapy. Kejík, Zdeněk, Jan Hajduch, Nikita Abramenko, Frédéric Vellieux, Kateřina Veselá, Jindřiška Leischner Fialová, Kateřina Petrláková, Kateřina Kučnirová, Robert Kaplánek, Ameneh Tatar, Markéta Skaličková, Michal Masařík, Petr Babula, Petr Dytrych, David Hoskovec, Pavel Martásek a Milan Jakubek. Communications Chemistry [online], 2024, 7(1), 180.
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A computational workflow for analysis of missense mutations in precision oncology. Khan, Rayyan Tariq, Petra Pokorna, Jan Stourac, Simeon Borko, Ihor Arefiev, Joan Planas-Iglesias, Adam Dobias, Gaspar Pinto, Veronika Szotkowska, Jaroslav Sterba, Ondrej Slaby, Jiri Damborsky, Stanislav Mazurenko a David Bednar. Journal of Cheminformatics [online], 2024, 16(1), 86.
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Analysis of mutations in precision oncology using the automated, accurate, and user-friendly web tool PredictONCO. Khan, Rayyan Tariq, Petra Pokorna, Jan Stourac, Simeon Borko, Adam Dobias, Joan Planas-Iglesias, Stanislav Mazurenko, Ihor Arefiev, Gaspar Pinto, Veronika Szotkowska, Jaroslav Sterba, Jiri Damborsky, Ondrej Slaby a David Bednar. Computational and Structural Biotechnology Journal [online], 2024 24, 734–738.
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Molecularly targeted protease-activated probes for visualization of glioblastoma: a comparison with 5-ALA. Konečná, Dora, Petr Výmola, Nikola Ternerová, Barbora Výmolová, Elena Garcia-Borja, Rosana Mateu, Filip Šroubek, Jan Pankrác, John C. Widen, Matthew Bogyo, David Netuka, Petr Bušek a Aleksi Šedo. Journal of Neurosurgery [online], 2024, 141(3), 602–613.
Soft micron-sized polypeptide microgels: preparation, crosslink density, topography and nanomechanics in swollen state. Kotko, Oleksii, Petr Šálek, Jana Dvořáková, Miroslava Dušková Smrčková, Ján Šomvársky, Jean Jacques Bonvent, Sérgio Brochsztain, Miroslav Šlouf a Vladimír Proks. Materials Advances [online],2024, 5(14), 5984–5997.
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The gray area of RQ-PCR-based measurable residual disease: subdividing the “positive, below quantitative range” category. Kotrova, Michaela, Eva Fronkova, Michael Svaton, Daniela Drandi, Felix Schön, Patricia Hoogeveen, Jeremy Hancock, Aneta Skotnicova, Anke Schilhabel, Cornelia Eckert, Emmanuelle Clappier, Gianni Cazzaniga, Beat W. Schäfer, Jacques J. M. Van Dongen, Matthias Ritgen, Christiane Pott, Vincent H. J. Van Der Velden, Jan Trka a Monika Brüggemann. Leukemia [online], 2024, 38(7), 1617–1620.
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Biodegradable Covalently Crosslinked Poly[N-(2-Hydroxypropyl) Methacrylamide] Nanogels: Preparation and Physicochemical Properties. Kousalová, Jana, Petr Šálek, Ewa Pavlova, Rafał Konefał, Libor Kobera, Jiří Brus, Olga Kočková a Tomáš Etrych. Polymers [online], 2024, 16(2), 263.
Chemosensitization of tumors via simultaneous delivery of STAT3 inhibitor and doxorubicin through HPMA copolymer-based nanotherapeutics with pH-sensitive activation. Kovář, M., V. Šubr, K. Běhalová, M. Studenovský, D. Starenko, J. Kovářová, P. Procházková, T. Etrych a L. Kostka. Nanomedicine: Nanotechnology, Biology and Medicine [online], 2024, 56, 102730.
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Carboxy-terminal polyglutamylation regulates signaling and phase separation of the Dishevelled protein. Kravec, Marek, Ondrej Šedo, Jana Nedvědová, Miroslav Micka, Marie Šulcová, Nikodém Zezula, Kristína Gömöryová, David Potěšil, Ranjani Sri Ganji, Sara Bologna, Igor Červenka, Zbyněk Zdráhal, Jakub Harnoš, Konstantinos Tripsianes, Carsten Janke, Cyril Bařinka a Vítězslav Bryja. The EMBO Journal [online], 2024, 43(22), 5635–5666.
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Quantitative and qualitative differences in the activation of a fibroblast growth factor receptor by different FGF ligands. Krzyscik, Mateusz A., Kelly Karl, Pooja Dudeja, Pavel Krejci a Kalina Hristova. Cytokine & Growth Factor Reviews [online], 2024, 78, 77–84.
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Vertical targeting of the PI3K/AKT pathway at multiple points is synergistic and effective for non-Hodgkin lymphoma. Kupcova, Kristyna, Jana Senavova, Filip Jura, Vaclav Herman, Anezka Rajmonova, Mariana Pacheco-Blanco, Tereza Chrbolkova, Iva Hamova, R. Eric Davis a Ondrej Havranek. Experimental Hematology & Oncology [online], 2024, 13(1), 108.
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Unveiling the dynamics and molecular landscape of a rare chronic lymphocytic leukemia subpopulation driving refractoriness: insights from single‐cell RNA sequencing. Kurucova, Terezia, Kamila Reblova, Pavlina Janovska, Jakub Pawel Porc, Veronika Navrkalova, Sarka Pavlova, Jitka Malcikova, Karla Plevova, Boris Tichy, Michael Doubek, Vitezslav Bryja, Jana Kotaskova a Sarka Pospisilova. Molecular Oncology [online], 2024, 1878–0261.13663.
Personalized dendritic cell vaccine in multimodal individualized combination therapy improves survival in high‐risk pediatric cancer patients. Kyr, Michal, Peter Mudry, Kristyna Polaskova, Lenka Zdrazilova Dubska, Regina Demlova, Jana Kubatova, Eva Hlavackova, Katerina Cerna Pilatova, Pavel Mazanek, Klara Vejmelkova, Vitezslav Dusek, Pavel Tinka, Martin Balaz, Tomas Merta, Zuzana Kuttnerova, Terezia Turekova, Zdenek Pavelka, Petra Pokorna, Hana Palova, Marie Mlnarikova, Marta Jezova, Renata Kellnerova, Sarka Kozakova, Ondrej Slaby, Dalibor Valik a Jaroslav Sterba. International Journal of Cancer [online], 2024, 155(8), 1443–1454.
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Wound healing: insights into autoimmunity, ageing, and cancer ecosystems through inflammation and IL-6 modulation. Lacina, Lukáš, Michal Kolář, Lucie Pfeiferová, Peter Gál a Karel Smetana. Frontiers in Immunology [online], 2024, 15, 1403570.
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A hybrid DDA/DIA-PASEF based assay library for a deep proteotyping of triple-negative breast cancer. Lapcik, Petr, Klara Synkova, Lucia Janacova, Pavla Bouchalova, David Potesil, Rudolf Nenutil a Pavel Bouchal. Scientific Data [online], 2024, 11(1), 794.
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Innovative synthesis of drug-like molecules using tetrazole as core building blocks. Li, Jingyao, Ajay L Chandgude, Qiang Zheng a Alexander Dömling. Beilstein Journal of Organic Chemistry [online], 2024, 20, 950–958.
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Navigating the redox landscape: reactive oxygen species in regulation of cell cycle. Mackova, Viktoria, Martina Raudenska, Hana Holcova Polanska, Milan Jakubek a Michal Masarik. Redox Report [online], 2024, 29(1), 2371173.
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Deciphering pathophysiological mechanisms underlying cystathionine beta-synthase-deficient homocystinuria using targeted metabolomics, liver proteomics, sphingolipidomics and analysis of mitochondrial function. Majtan, Tomas, Thomas Olsen, Jitka Sokolova, Jakub Krijt, Michaela Křížková, Tomoaki Ida, Tamás Ditrói, Hana Hansikova, Ondrej Vit, Jiri Petrak, Ladislav Kuchař, Warren D. Kruger, Péter Nagy, Takaaki Akaike a Viktor Kožich. Redox Biology [online], 2024, 73, 103222.
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Cyclin dependent kinase 4/6 inhibitor palbociclib synergizes with BCL2 inhibitor venetoclax in experimental models of mantle cell lymphoma without RB1 deletion. Malarikova, Diana, Radek Jorda, Kristyna Kupcova, Jana Senavova, Alexandra Dolnikova, Eva Pokorna, Dmitry Kazantsev, Kristina Nozickova, Dana Sovilj, Celine Bellanger, David Chiron, Ladislav Andera, Vladimir Krystof, Miroslav Strnad, Karel Helman, Magdalena Klanova, Marek Trneny, Ondrej Havranek a Pavel Klener. Experimental Hematology & Oncology [online], 2024, 13(1), 34.
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ERIC recommendations for TP53 mutation analysis in chronic lymphocytic leukemia—2024 update. Malcikova, Jitka, Sarka Pavlova, Panagiotis Baliakas, Thomas Chatzikonstantinou, Eugen Tausch, Mark Catherwood, Davide Rossi, Thierry Soussi, Boris Tichy, Arnon P. Kater, Carsten U. Niemann, Frederic Davi, Gianluca Gaidano, Stephan Stilgenbauer, Richard Rosenquist, Kostas Stamatopoulos, Paolo Ghia a Sarka Pospisilova. Leukemia [online], 2024, 38(7), 1455–1468.
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Small nucleolar RNA expression profiles: A potential prognostic biomarker for non-viral Hepatocellular carcinoma. Mallela, Venkata Ramana, Phanindra Babu Kasi, Dattatrya Shetti, Andriy Trailin, Lenka Cervenkova, Richard Palek, Ondřej Daum, Vaclav Liska, Kari Hemminki a Filip Ambrozkiewicz. Non-coding RNA Research [online], 2024, 9(4), 1133–1139.
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PPM1D activity promotes the replication stress caused by cyclin E1 overexpression. Martinikova, Andra S., Miroslav Stoyanov, Anna Oravetzova, Yannick P. Kok, Shibo Yu, Jana Dobrovolna, Pavel Janscak, Marcel Van Vugt a Libor Macurek. Molecular Oncology [online], 2024, 18(1), 6–20.
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Synthesis and Structure Optimization of Star Copolymers as Tunable Macromolecular Carriers for Minimal Immunogen Vaccine Delivery. Mixová, Gabriela, Eva Tihlaříková, Yaling Zhu, Lucie Schindler, Ladislav Androvič, Lucie Kracíková, Eliška Hrdá, Bedřich Porsch, Michal Pechar, Christopher M. Garliss, David Wilson, Hugh C. Welles, Jake Holechek, Qiuyin Ren, Geoffrey M. Lynn, Vilém Neděla a Richard Laga. Bioconjugate Chemistry [online], 2024, 35(8), 1218–1232
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Identification of furo[2,3-d]pyrimidin-4-ylsulfanyl-1,3,4-thiadiazole derivatives as novel FLT3-ITD inhibitors. Moradi, Mahfam, Alireza Mousavi, Eva Řezníčková, Fariba Peytam, Miroslav Peřina, Veronika Vojáčková, Loghman Firoozpour, Radek Jorda, Jiří Grúz, Zahra Emamgholipour, Seyed Esmaeil Sadat-Ebrahimi, Vladimír Kryštof a Alireza Foroumadi. European Journal of Medicinal Chemistry [online], 2024, 280, 116962.
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Integrative NGS testing reveals clonal dynamics of adverse genomic defects contributing to a natural progression in treatment‐naïve CLL patients. Navrkalova, Veronika, Karla Plevova, Lenka Radova, Jakub Porc, Karol Pal, Jitka Malcikova, Sarka Pavlova, Michael Doubek, Anna Panovska, Jana Kotaskova a Sarka Pospisilova. British Journal of Haematology [online], 2024, 204(1), 240–249.
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Discovery of Two Highly Selective Structurally Orthogonal Chemical Probes for Activin Receptor-like Kinases 1 and 2. Němec, Václav, Marek Remeš, Petr Beňovský, Michael C. Böck, Eliška Šranková, Jong Fu Wong, Julien Cros, Eleanor Williams, Lap Hang Tse, David Smil, Deeba Ensan, Methvin B. Isaac, Rima Al-Awar, Regina Gomolková, Vlad-Constantin Ursachi, Bohumil Fafílek, Zuzana Kahounová, Ráchel Víchová, Ondřej Vacek, Benedict-Tilman Berger, Carrow I. Wells, Cesear R. Corona, James D. Vasta, Matthew B. Robers, Pavel Krejci, Karel Souček, Alex N. Bullock, Stefan Knapp a Kamil Paruch. Journal of Medicinal Chemistry [online], 2024, 67(15), 12632–12659.
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Structural, Biochemical, and Computational Characterization of Sulfamides as Bimetallic Peptidase Inhibitors. Novakova, Zora, Zahra Aliakbar Tehrani, Radek Jurok, Lucia Motlova, Zsofia Kutil, Jiri Pavlicek, Shivam Shukla, Cindy J. Choy, Barbora Havlinova, Petra Baranova, Clifford E. Berkman, Martin Kuchar, Jiri Cerny a Cyril Barinka. Journal of Chemical Information and Modeling [online], 2024, 64(3), 1030–1042.
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FoxO1/Rictor axis induces a nongenetic adaptation to ibrutinib via Akt activation in chronic lymphocytic leukemia. Ondrisova, Laura, Vaclav Seda, Krystof Hlavac, Petra Pavelkova, Eva Hoferkova, Giorgia Chiodin, Lenka Kostalova, Gabriela Mladonicka Pavlasova, Daniel Filip, Josef Vecera, Pedro Faria Zeni, Jan Oppelt, Zuzana Kahounova, Rachel Vichova, Karel Soucek, Anna Panovska, Karla Plevova, Sarka Pospisilova, Martin Simkovic, Filip Vrbacky, Daniel Lysak, Stacey M. Fernandes, Matthew S. Davids, Alba Maiques-Diaz, Stella Charalampopoulou, Jose I. Martin-Subero, Jennifer R. Brown, Michael Doubek, Francesco Forconi, Jiri Mayer a Marek Mraz. Journal of Clinical Investigation [online], 2024, 134(23), e173770.
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Galectin-3-Binding Protein Inhibits Extracellular Heparan 6-O-Endosulfatase Sulf-2. Panigrahi, Aswini, Julius Benicky, Reem Aljuhani, Pritha Mukherjee, Zora Nováková, Cyril Bařinka a Radoslav Goldman. Molecular & Cellular Proteomics [online], 2024, 23(7), 100793.
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Metabolomics and proteomics in pheochromocytoma and paraganglioma: Translating biochemistry and biology to bedside. PETRAK, Jiri, Sergei G. TEVOSIAN, Susan RICHTER a Hans K. GHAYEE. Best Practice & Research Clinical Endocrinology & Metabolism [online], 2024, 38(6), 101935.
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Structural Optimization of Azacryptands for Targeting Three‐Way DNA Junctions. Pipier, Angélique, Titouan Chetot, Apollonia Kalamatianou, Nicolas Martin, Maëlle Caroff, Sébastien Britton, Nicolas Chéron, Lukáš Trantírek, Anton Granzhan a David Monchaud. Angewandte Chemie International Edition [online], 2024, 63(36), e202409780.
Real-World Performance of Integrative Clinical Genomics in Pediatric Precision Oncology. Pokorna, Petra, Hana Palova, Sona Adamcova, Robin Jugas, Dagmar Al Tukmachi, Michal Kyr, Dana Knoflickova, Katerina Kozelkova, Vojtech Bystry, Sona Mejstrikova, Tomas Merta, Karolina Trachtova, Eliska Podlipna, Peter Mudry, Zdenek Pavelka, Viera Bajciova, Pavel Tinka, Marie Jarosova, Tina Catela Ivkovic, Sibylle Madlener, Karol Pal, Natalia Stepien, Lisa Mayr, Boris Tichy, Klara Drabova, Marta Jezova, Sarka Kozakova, Jitka Vanackova, Lenka Radova, Karin Steininger, Christine Haberler, Johannes Gojo, Jaroslav Sterba a Ondrej Slaby. Laboratory Investigation [online], 2024, 104(12), 102161.
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Bringing to Light the Importance of the miRNA Methylome in Colorectal Cancer Prognosis Through Electrochemical Bioplatforms. Povedano, Eloy, Víctor Ruiz-Valdepeñas Montiel, Ravery Sebuyoya, Rebeca M. Torrente-Rodríguez, Maria Garranzo-Asensio, Ana Montero-Calle, José M. Pingarrón, Rodrigo Barderas, Martin Bartosik a Susana Campuzano. Analytical Chemistry [online], 2024, 96(11), 4580–4588.
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Single-cell profiling of surface glycosphingolipids opens a new dimension for deconvolution of breast cancer intratumoral heterogeneity and phenotypic plasticity. Procházková, Jiřina, Radek Fedr, Barbora Hradilová, Barbora Kvokačková, Josef Slavík, Ondrej Kováč, Miroslav Machala, Pavel Fabian, Jiří Navrátil, Simona Kráčalíková, Monika Levková, Petra Ovesná, Jan Bouchal a Karel Souček. Journal of Lipid Research [online], 2024, 65(9), 100609.
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Highly hydrophilic methacrylamide-based copolymers as precursors for polymeric nanomedicines containing anthracyclines. Pytlíková, Sára, Michal Pechar, Petr Chytil, Martin Studenovský, Robert Pola, Lenka Kotrchová, Rafal Konefał, Lucie Čtveráčková, Richard Laga, Jan Pankrác, Shanghui Gao, Benchun Jiang, Kai Yang, Jun Fang, Marcela Filipová a Tomáš Etrych. European Polymer Journal [online], 2024, 205, 112756.
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Revising pathogenesis of AP1S1-related MEDNIK syndrome: a missense variant in the AP1S1 gene as a causal genetic lesion. Rackova, Marketa, Rafael Mattera, Michael Svaton, Filip Fencl, Veronika Kanderova, Karolina Spicakova, Sang Yoon Park, Ondrej Fabian, Miroslav Koblizek, Eva Fronkova, Juan S. Bonifacino a Karolina Skvarova Kramarzova. Journal of Molecular Medicine [online], 2024, 102(11), 1343–1353.
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Constitutional and acquired genetic variants in ARID5B in pediatric B‐cell precursor acute lymphoblastic leukemia. Ragnarsson, Charlotte, Minjun Yang, Larissa Helena Moura‐Castro, Efe Aydin, Rebeqa Gunnarsson, Linda Olsson‐Arvidsson, Henrik Lilljebjörn, Thoas Fioretos, Nicolas Duployez, Marketa Zaliova, Jan Zuna, Anders Castor, Bertil Johansson a Kajsa Paulsson. Genes, Chromosomes and Cancer [online], 2024, 63(5), e23242.
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JUN mediates the senescence associated secretory phenotype and immune cell recruitment to prevent prostate cancer progression. Redmer, Torben, Martin Raigel, Christina Sternberg, Roman Ziegler, Clara Probst, Desiree Lindner, Astrid Aufinger, Tanja Limberger, Karolina Trachtova, Petra Kodajova, Sandra Högler, Michaela Schlederer, Stefan Stoiber, Monika Oberhuber, Marco Bolis, Heidi A. Neubauer, Sara Miranda, Martina Tomberger, Nora S. Harbusch, Ines Garces De Los Fayos Alonso, Felix Sternberg, Richard Moriggl, Jean-Philippe Theurillat, Boris Tichy, Vojtech Bystry, Jenny L. Persson, Stephan Mathas, Fritz Aberger, Birgit Strobl, Sarka Pospisilova, Olaf Merkel, Gerda Egger, Sabine Lagger a Lukas Kenner. Molecular Cancer [online], 2024, 23(1), 114.
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Click estradiol dimers with novel aromatic bridging units: synthesis and anticancer evaluation. Řehulka, Jiří, Michal Jurášek, Pavel Dráber, Aleksandra Ivanová, Soňa Gurská, Kateřina Ječmeňová, Olena Mokshyna, Marián Hajdúch, Pavel Polishchuk, Pavel B. Drašar a Petr Džubák. Journal of Enzyme Inhibition and Medicinal Chemistry [online], 2024, 39(1), 2367139.
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Iridium‐based Polymeric Multifunctional Imaging Tools for Biochemistry. Sansee, Anuson, Libor Kostka, Adéla Marcalíková, Júlia Kudláčová, František Sedlák, Lenka Kotrchová, Pavel Šácha, Tomáš Etrych a Filip Kielar. ChemPlusChem [online], 2024, 89(5), e202300647.
Parallel Metabolomics and Lipidomics of a PSMA/GCPII Deficient Mouse Model Reveal Alteration of NAAG Levels and Brain Lipid Composition. Sedlák, František, Aleš Kvasnička, Barbora Marešová, Radana Brumarová, Dana Dobešová, Kateřina Dostálová, Karolína Šrámková, Martin Pehr, Pavel Šácha, David Friedecký a Jan Konvalinka. ACS Chemical Neuroscience [online], 2024, 15(7), 1342–1355.
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MiR-4646-5p Acts as a Tumor-Suppressive Factor in Triple Negative Breast Cancer and Targets the Cholesterol Transport Protein GRAMD1B. Katharina Jonas, Felix Prinz, Manuela Ferracin, Katarina Krajina, Alexander Deutsch, Tobias Madl, Beate Rinner, Ondřej Slabý, Christiane Klec a Martin Pichler. Non-coding RNA. Švýcarsko: MDPI, 2024, roč. 10, č. 1, s. 1-24.
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ERIC recommendations for TP53 mutation analysis in chronic lymphocytic leukemia-2024 update. Jitka Malčíková, Šárka Pavlová, Panagiotis Baliakas, Thomas Chatzikonstantinou, Eugen Tausch, Mark Catherwood, Davide Rossi, Thierry Soussi, Boris Tichy, Arnon P Kater, Carsten U Niemann, Frederic Davi, Gianluca Gaidano, Stephan Stilgenbauer, Richard Rosenquist, Kostas Stamatopoulos, Paolo Ghia a Šárka Pospíšilová. Leukemia. London: Nature Publishing Group, 2024, 14 s.
doi: 10.1038/s41375-024-02267-x. PMID: 38755420
PredictONCO: a web tool supporting decision-making in precision oncology by extending the bioinformatics predictions with advanced computing and machine learning. Jan Štourač, Simeon Borko, Rayyan Tariq Khan, Petra Pokorná, Adam Dobiáš, Joan Planas Iglesias, Stanislav Mazurenko, José Gaspar Rangel Pamplona Pizarro Pinto, Veronika Szotkowská, Jaroslav Štěrba, Ondřej Slabý, Jiří Damborský a David Bednář. Briefings in Bioinformatics. Oxford University Press, 2024, roč. 25, č. 1, s. 1-10.
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A replicating LCMV-based vaccine for the treatment of solid tumors. Purde Mette-Triin, Jovana Cupovic, Yannick A Palmowski, Ahmad Makky, Sarah Schmidt, Alexander Rochwarger, Fabienne Hartmann, Felix Stemeseder, Alexander Lercher, Abdou Marie-Therese, David Bomze, Lenka Bešše, Fiamma Berner, Thomas Tüting, Michael Hölzel, Andreas Bergthaler, Stefan Kochanek, Burkhard Ludewig, Henning Lauterbach, Klaus K Orlinger, Tobias Bald, Andrea Schietinger, Christian Schürch, Sandra S Ring a Lukas Flatz. Molecular Therapy. Cambridge: Cell Press, 2024, roč. 32, č. 2, s. 426-439.
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A sodium/potassium switch for G4-prone G/C-rich sequences. Yu Luo, Martina Lenarčič Živkovic, Jiawei Wang, Jan Ryneš, Silvie Trantírková, Lukáš Trantírek, Daniela Verga a Jean-Louis Mergny. Nucleic acids research. Oxford: Oxford University Press, 2024, roč. 52, č. 1, s. 448-461.
doi: 10.1093/nar/gkad1073. PMID: 37986223
Global interactome mapping reveals pro-tumorigenic interactions of NF-κB in breast cancer. Petr Lapčík, R. Greg Stacey, David Potěšil, Petr Kulhánek, Leonard J. Foster a Pavel Bouchal. Molecular and Cellular Proteomics. Elsevier, 2024, roč. 23, č. 4, s. 1-20.
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Why are not all eligible chronic myeloid leukemia patients willing to attempt tyrosine kinase inhibitor discontinuation? A Czech nationwide analysis related to the TKI stopping trial HALF. Daniela Žáčková, Lukáš Semerád, Edgar Faber, Hana Klamová, Lukáš Stejskal, Petra Bělohlávková, Michal Karas, Eduard Cmunt, Olga Černá, Jiřina Procházková, Petra Čičátková, Anežka Kvetková, Tomáš Horňák, Ivana Skoumalová, Dana Srbová, Cyril Šálek, David Buffa, Jaroslava Voglová, Tomáš Jurček, Adam Folta, Ivana Ježíšková, Hana Žižková, Kateřina Machová Poláková, Tomáš Papajík, Pavel Žák, Pavel Jindra, Adam Svobodník, Radka Štěpánová a Jiří Mayer. Leukemia. London: Springer Nature, 2024, roč. 38, č. 4, s. 893-897.
doi: 10.1038/s41375-024-02215-9. PMID: 38472478
Unilateral hippocampal sparing during whole brain radiotherapy for multiple brain metastases: narrative and critical review. Petr Pospíšil, Ludmila Hynková, Lucie Hnidáková, Jana Maistryszinová, Pavel Šlampa a Tomáš Kazda. Frontiers in Oncology. Lausanne: Frontiers Media SA, 2024, roč. 14, January 2024, s. 1-11.
doi: 10.3389/fonc.2024.1298605. PMID: 38327742
Hippocampal subfield volumetric changes after radiotherapy for brain metastases. Klára Holíková, Iveta Selingerova, Petr Pospíšil, Martin Bulik, Ludmila Hynková, Ivana Kolouskova, Lucie Hnidakova, Petr Burkoň, Marek Slávik, Jiří Šána, Tomáš Holeček, Jiří Vaníček, Pavel Šlampa, Radim Jančálek a Tomáš Kazda. Neuro-Oncology Advances. Oxford: Oxford Univ Press, 2024, roč. 6, č. 1, 9 s.
doi: 10.1093/noajnl/vdae040. PMID: 38645488
Investigation of long non-coding RNAs in extracellular vesicles from low-volume blood serum specimens of colorectal cancer patients. Marie Boudná, Táňa Macháčková, Petra Vychytilová, Karolína Trachtová, Renata Bartošová, Tina Catela Ivković, Dagmar Al Tukmachi, Robin Jugas, Lucie Pifková, Jana Orlíčková, Jan Kotouček, Marketa Pavlikova, Milana Šachlová, Lucia Bohovicová, Teodor Staněk, Jana Halámková, Igor Kiss, Tomáš Grolich, Martin Svoboda, Zdeněk Kala, Kamila Součková a Ondřej Slabý. Clinical and Experimental Medicine. Milan: Springer-Verlag Italia SRL, 2024, roč. 24, č. 1, s. 1-14.
doi: 10.1007/s10238-024-01323-1. PMID: 38568288
Real-world data on diagnostics, treatment and outcomes of patients with hairy cell leukemia: The HCL-CLLEAR study. Anna Panovská, Pavel Zak, Tereza Jurkova, Tomáš Arpáš, Yvona Brychtová, Alžběta Vašíčková, Viera Hrabáčková, Adéla Prchlíková, Martina Filipová a Michael Doubek. Hematological Oncology. Hoboken: Wiley-Blackwell, 2024, roč. 42, č. 3, s. 1-9.
doi: 10.1002/hon.3280. PMID: 38741354
IκBε deficiency accelerates disease development in chronic lymphocytic leukemia. Jessica Bordini, Chiara Lenzi, Michela Frenquelli, Alessia Morabito, Athanasios Pseftogas, Daniela Belloni, Larry Mansouri, George Tsiolas, Eleonora Perotta, Pamela Ranghetti, Francesca Gandini, Francesca Genova, Daniel Hagerstrand, Georgios Gavriilidis, Sofoklis Keisaris, Nikolaos Pechlivanis, Frederic Davi, Neil E Kay, Anton W Langerak, Šárka Pospíšilová, Lydia Scarfo, Antonios Makris, Fotis E Psomopoulos, Kostas Stamatopoulos, Richard Rosenquist, Alessandro Campanella a Paolo Ghia. Leukemia. London: Nature Publishing Group, 2024, 12 s.
doi: 10.1038/s41375-024-02236-4.
Precision immuno-oncology approach for four malignant tumors in siblings with constitutional mismatch repair deficiency syndrome. Hana Pálová, Anirban Das, Petra Pokorná, Viera Bajčiová, Zdenek Pavelka, Marta Ježová, Karol Pál, Jose R Dimayacyac, Logine Negm, Lucie Stengs, Vanessa Bianchi, Klára Vejmělková, Kristýna Nosková, Marie Jarošová, Soňa Mejstříková, Peter Múdry, Michal Kýr, Tomáš Merta, Pavel Tinka, Klára Drábová, Štefánia Aulická, Robin Jugas, Uri Tabori, Ondřej Slabý a Jaroslav Štěrba. NPJ Precision Oncology. Belin: Nature Portfolio, 2024, roč. 8, č. 1, s. 1-9.
doi: 10.1038/s41698-024-00597-8.
Strategies for labelling of exogenous and endogenous extracellular vesicles and their application for in vitro and in vivo functional studies. Marie Boudná, Andres Delgado Campos, Petra Vychytilová, Táňa Macháčková, Ondřej Slabý a Kamila Součková. Cell Communication and Signaling. London: BMC, 2024, roč. 22, č. 1, s. 1-15.
doi: 10.1186/s12964-024-01548-3. PMID: 38461237
Toxicity of external beam accelerated partial-breast irradiation (APBI) in adjuvant therapy of early-stage breast cancer: prospective randomized study. Petr Burkoň, Iveta Selingerová, Marek Slávik, Miloš Holánek, Miroslav Vrzal, Oldřich Coufal, Kateřina Poláchová, Petr Müller, Pavel Šlampa a Tomáš Kazda. Radiation Oncology. BMC: Elsevier, 2024, roč. 19, č. 1, s. 1-12.
doi: 10.1186/s13014-024-02412-x. PMID: 38310249
FasL impacts Tgfb signaling in osteoblastic cells. Adela Kratochvilova, Lucia Knopfová, Janka Gregorkova, Reinhard Gruber, Eva Janeckova, Yang Chai a Eva Matalova. Cells & Development. Elsevier B.V., 2024, 6 s.
doi: 10.1016/j.cdev.2024.203929. PMID: 38810946
InVADo: Interactive Visual Analysis of Molecular Docking Data. Marco Schäfer, Nicolas Brich, Jan Byška, Sérgio Manuel Marques, David Bednář, Philipp Thiel, Barbora Kozlíková a Michael Krone. IEEE Transactions on Visualization and Computer Graphics. IEEE Computer Society, 2024, roč. 30, č. 4, s. 1984-1997.
doi: 10.1109/TVCG.2023.3337642. PMID: 38019636
Caspase-9 Is a Positive Regulator of Osteoblastic Cell Migration Identified by diaPASEF Proteomics. Kamila Říhová, Petr Lapčík, Barbora Veselá, Lucia Knopfová, David Potěšil, Jana Pokludová, Jan Šmarda, Eva Matalová, Pavel Bouchal a Petr Beneš. Journal of Proteome Research. American Chemical Society, 2024, 13 s.
doi: 10.1021/acs.jproteome.3c00641. PMID: 38498986
Emerging roles of prominin-1 (CD133) in the dynamics of plasma membrane architecture and cell signaling pathways in health and disease. Petr Pleskač, Christine A. Fargeas, Renata Veselská, Denis Corbeil a Jan Škoda. Cellular and Molecular Biology Letters. BMC, 2024, roč. 29, č. 1, s. 1-47.
doi: 10.1186/s11658-024-00554-0. PMID: 38532366
Challenges with hippocampal MR spectroscopy as a surrogate for pre-radiotherapy assessment of neurocognitive impairment in patients with brain metastasis. Iveta Selingerová, Klára Holíková, Tomas Chodur, Ludmila Hynková, Petr Pospíšil, Martin Bulik, Renata Belanová, Kamila Siffelova, Ivana Koloušková, Marek Slávik, Petr Burkoň, Roman Hrstka, Radim Jančálek, Jiří Šána, Pavel Šlampa a Tomáš Kazda. Biomedical Papers, Olomouc: Palacky University. Olomouc: Palacky University, 2024, 8 s.
doi: 10.5507/bp.2024.012. PMID: 38623639
Blockage of BCL-XL overcomes venetoclax resistance across BCL2-positive lymphoid malignancies irrespective of BIM status. Alexandra Dolnikova, Dmitry Kazanstev, Magdalena Klanova, Eva Pokorna, Dana Sovilj, Cristina Daniela Kelemen, Liliana Tuskova, Eva Hoferková, Marek Mráz, Karel Helman, Nikola Curik, Katerina Machova Polakova, Ladislav Anděra, Marek Trněný a Pavel Klener. Blood Advances. Amsterdam: Elsevier, 2024, roč. 10.1182/bl.
doi: 10.1182/bloodadvances.2024012906. PMID: 38713893
Stromal cells engineered to express T cell factors induce robust CLL cell proliferation in vitro and in PDX co-transplantations allowing the identification of RAF inhibitors as anti-proliferative drug. Eva Hoferková, Václav Šeda, Soňa Cesnáriková, Jan Verner, Tomáš Loja, Květoslava Matulová, Hana Skuhrová Francová, Eva Ondroušková, Daniel Filip, Nicolas Blavet, Miroslav Boudný, Gabriela Mladonická Pavlasová, Josef Večeřa, Laura Ondrišová, Petra Pavelková, Kryštof Hlaváč, Lenka Košťálová, Androniki Michaelou, Šárka Pospíšilová, Jana Dorazilová, Václav Chochola, Josef Jaroš, Michael Doubek, Marie Jarošová, Aleš Hampl, Lucy Vojtová, Leoš Křen, Jiří Mayer a Marek Mráz. Leukemia. London: Springer Nature, 2024.
doi: 10.1038/s41375-024-02284-w. PMID: 38877102
Unraveling the epigenetic landscape of pulmonary arterial hypertension: implications for personalized medicine development. Jaydev Dave, Vineeta Jagana, Radoslav Janostiak, Malik Bisserier. J Transl Med. 2023 Jul 17;21(1):477.
doi: 10.1186/s12967-023-04339-5. PMID: 37461108; PMCID: PMC10353122.
Sequencing-based analysis of clonal evolution of 25 mantle cell lymphoma patients at diagnosis and after failure of standard immunochemotherapy. Jana Karolová, Dmitry Kazantsev, Michael Svatoň, Liliana Tušková, Kristina Forsterová, Diana Maláriková, Kateřina Benešová, Tomáš Heizer, Alexandra Dolníková, Magdalena Klánová, Lucie Winkowska, Karla Svobodová, Jan Hojný, Eva Krkavcová, Eva Froňková, Zuzana Zemanová, Marek Trněný, Pavel Klener. Am J Hematol. 2023; 98(10): 1627-1636.
doi:10.1002/ajh.27044. PMID: 37605345
Early-Onset Ovarian Cancer <30 Years: What Do We Know about Its Genetic Predisposition? Klara Horackova, Marketa Janatova, Petra Kleiblova, Zdenek Kleibl and Jana Soukupova. Int J Mol Sci. 2023 Nov 30;24(23):17020.
doi: 10.3390/ijms242317020. PMID: 38069345; PMCID: PMC10707471.
Total neoadjuvant therapy in rectal cancer: the evidence and expectations. Ludmila Boublikova, Alena Novakova, Jaromir Simsa, Radka Lohynska. Critical Reviews in Oncology/hematology. 2023 Dec;192:104196.
doi: 10.1016/j.critrevonc.2023.104196. PMID: 37926376.
Combination of quinoxaline with pentamethinium system: Mitochondrial staining and targeting. Zdeněk Kejík, Nela Koubková, Lucie Krčová, David Sýkora, Nikita Abramenko, Kateřina Veselá, Robert Kaplánek, Jan Hajduch, Magdalena Houdová Megová, Petr Bušek, Aleksi Šedo, Lukáš Lacina, Karel Smetana Jr., Pavel Martásek, Milan Jakubek. Bioorg Chem. 2023 Dec;141:106816.
doi: 10.1016/j.bioorg.2023.106816. PMID: 37716274.
TET protein inhibitors: Potential and limitations. Robert Kaplánek, Zdeněk Kejík, Jan Hajduch, Kateřina Veselá, Kateřina Kučnirová, Markéta Skaličková, Anna Venhauerová, Božena Hosnedlová, Róbert Hromádka, Petr Dytrych, Petr Novotný, Nikita Abramenko, Veronika Antonyová, David Hoskovec, Petr Babula, Michal Masařík, Pavel Martásek, Milan Jakubek.. Biomed Pharmacother. 2023 Oct;166:115324.
doi: 10.1016/j.biopha.2023.115324. PMID: 37598475.
Fibroblast activation protein as a potential theranostic target in brain metastases of diverse solid tumours. Michal Zubaľ, Barbora Výmolová, Ivana Matrasová, Petr Výmola, Jana Vepřková, Martin Syrůček, Robert Tomáš, Zdislava Vaníčková, Evžen Křepela, Dora Konečná, Petr Bušek, Aleksi Šedo. Pathology. 2023 Oct;55(6):806-817.
doi: 10.1016/j.pathol.2023.05.003. PMID: 37419841.
Tuning polymer-blood and polymer-cytoplasm membrane interactions by manipulating the architecture of poly(2-oxazoline) triblock copolymers. Volodymyr Lobaz, Veronika Liščáková, František Sedlák, Dominik Musil, Svetlana Lukáš Petrova, Ivana Šeděnková, Jiří Pánek, Jan Kučka, Rafał Konefał, Eva Tihlaříková, Vilém Neděla, Jan Pankrác, Luděk Šefc, Martin Hrubý, Pavel Šácha, Petr Štěpánek. Colloids Surf B Biointerfaces. 2023 Nov; 231:113564.
doi: 10.1016/j.colsurfb.2023.113564. PMID: 37742364.
Dual detection system for cancer-associated point mutations assisted by a multiplexed LNA-based amperometric bioplatform coupled with rolling circle amplification, Ravery Sebuyoya, Alejandro Valverde, Ludmila Moranova, Johana Strmiskova, Roman Hrstka, Víctor Ruiz-Valdepeñas Montiel, José M. Pingarrón, Rodrigo Barderas, Susana Campuzano, Martin Bartosik. Sensors and Actuators B: Chemical, Volume 394, 2023, 134375.
doi: 10.1016/j.snb.2023.134375.
Primary assessment of medicines for expected migrastatic potential with holographic incoherent quantitative phase imaging. Markéta Šuráňová, Miroslav Ďuriš, Irena Štenglová Netíková, Jan Brábek, Tomáš Horák, Veronika Jůzová, Radim Chmelík, Pavel Veselý. Biomed Opt Express. 2023 May 16;14(6):2689-2708.
doi: 10.1364/BOE.488630. PMID: 37342686; PMCID: PMC10278600.
Phosphorylation of tyrosine 90 in SH3 domain is a new regulatory switch controlling Src kinase. Lenka Koudelková, Markéta Pelantová, Zuzana Brůhová, Martin Sztacho, Vojtěch Pavlík, Dalibor Pánek, Jakub Gemperle, Pavel Talacko, Jan Brábek, Daniel Rösel. Elife. 2023 Jul 10;12:e82428.
doi: 10.7554/eLife.82428. PMID: 37428018; PMCID: PMC10361714.
Th1/interferon-γ bias in 22q11.2 deletion syndrome is driven by memory T cells and exacerbated by IL-7. Ondrej Vladyka, Petra Vrabcova, Michaela Reiterova, Zuzana Parackova, Robert Haesler, Anna Sediva, Tomas Kalina, Adam Klocperk. Clin Immunol. 2023 Nov; 256:109793.
doi: 10.1016/j.clim.2023.109793. PMID: 37776967.
Posttreatment positivity of BCR::ABL1 in acute lymphoblastic leukemia: Should we keep track? Jan Zuna, Lenka Hovorkova, Justina Krotka, Lucie Winkowska, Zbynek Novak, Lucie Sramkova, Jan Stary, Jan Trka, Giovanni Cazzaniga, Gunnar Cario, Marketa Zaliova. Am J Hematol. 2023 Oct;98(10):E269-E271.
doi: 10.1002/ajh.27022. PMID: 37449465.
Chimeric JAK2 Kinases Trigger Non-uniform Changes of Cellular Metabolism in BCR-ABL1-like Childhood ALL. Julius Lukes Jr, Eliska Potuckova, Natividad Alquezar-Artieda, Ivana Hermanova, Sladjana Kosanovic, Katerina Hlozkova, Meritxell Alberich Jorda, Jan Zuna, Jan Trka, Daniel A Tennant, Martin Stanulla, Marketa Zaliova, Julia Starkova. Hemasphere. 2023 Aug 23;7(9):e946.
doi: 10.1097/HS9.0000000000000946. PMID: 37637992; PMCID: PMC10448929.
Hybrid Macromolecular Constructs as a Platform for Spectral Nanoprobes for Advanced Cellular Barcoding in Flow Cytometry. Júlia Kudláčová, Daniela Kužílková, František Bárta, Naděžda Brdičková, Adéla Vávrová, Libor Kostka, Ondřej Hovorka, Tomáš Kalina, Tomáš Etrych. Macromol Biosci. 2023 Sep 11:e2300306.
doi: 10.1002/mabi.202300306. PMID: 37691533.
Survival in melanoma in the nordic countries into the era of targeted and immunological therapies. Filip Tichanek, Asta Försti, Akseli Hemminki, Otto Hemminki, Kari Hemminki. Eur J Cancer. 2023 Jun;186:133-141.
doi: 10.1016/j.ejca.2023.03.019. PMID: 37068406; PMCID: PMC10209636.
Survival in Lung Cancer in the Nordic Countries Through A Half Century. Filip Tichanek, Asta Försti, Otto Hemminki, Akseli Hemminki, Kari Hemminki. Clin Epidemiol. 2023 May 1;15:503-510.
doi: 10.2147/CLEP.S406606. PMID: 37153073; PMCID: PMC10162394.
The dynamics of telomere length in primary and metastatic colorectal cancer lesions. Michal Kroupa, Ondrej Kubecek, Kristyna Tomasova, Petr Hanak, Marketa Krupova, Klara Cervena, Anna Siskova, Jachym Rosendorf, Petr Hosek , Ludmila Vodickova, Pavel Vodicka, Vaclav Liska, Stanislav John, Veronika Vymetalkova, Jiri Petera. Sci Rep. 2023 Jun 5;13(1):9097.
doi: 10.1038/s41598-023-35835-9. PMID: 37277368; PMCID: PMC10241861.
A Fecal MicroRNA Signature by Small RNA Sequencing Accurately Distinguishes Colorectal Cancers: Results From a Multicenter Study. Barbara Pardini, Giulio Ferrero, Sonia Tarallo, Gaetano Gallo, Antonio Francavilla, Nicola Licheri, Mario Trompetto, Giuseppe Clerico, Carlo Senore, Sergio Peyre, Veronika Vymetalkova, Ludmila Vodickova, Vaclav Liska, Ondrej Vycital, Miroslav Levy, Peter Macinga, Tomas Hucl, Eva Budinska, Pavel Vodicka, Francesca Cordero, Alessio Naccarati. Gastroenterology. 2023 Sep;165(3):582-599.e8.
doi: 10.1053/j.gastro.2023.05.037. PMID: 37263306.
Autoimmune diseases as comorbidities for liver, gallbladder, and biliary duct cancers in Sweden. Kari Hemminki, Kristina Sundquist, Jan Sundquist, Asta Försti, Vaclav Liska, Akseli Hemminki, Xinjun Li. Cancer. 2023 Jan 30.
doi: 10.1002/cncr.34663. PMID: 36715017.
Type I interferon signaling in malignant blasts contributes to treatment efficacy in AML patients. Peter Holicek, Iva Truxova, Jana Rakova, Cyril Salek, Michal Hensler, Marek Kovar, Milan Reinis, Romana Mikyskova, Josef Pasulka, Sarka Vosahlikova, Hana Remesova, Iva Valentova, Daniel Lysak, Monika Holubova, Petr Kaspar, Jan Prochazka, Lenka Kasikova, Radek Spisek, Lorenzo Galluzzi, Jitka Fucikova. Cell Death Dis. 2023 Mar 24;14(3):209.
doi: 10.1038/s41419-023-05728-w. PMID: 36964168; PMCID: PMC10039058.
Regulatory T cells suppress the formation of potent KLRK1 and IL-7R expressing effector CD8 T cells by limiting IL-2. Oksana Tsyklauri, Tereza Chadimova, Veronika Niederlova, Jirina Kovarova, Juraj Michalik, Iva Malatova, Sarka Janusova, Olha Ivashchenko, Helene Rossez, Ales Drobek, Hana Vecerova, Virginie Galati, Marek Kovar, Ondrej Stepanek. Elife. 2023 Jan 27;12:e79342.
doi: 10.7554/eLife.79342. PMID: 36705564; PMCID: PMC9977273.
IL-2-driven CD8+ T cell phenotypes: implications for immunotherapy. Veronika Niederlova, Oksana Tsyklauri, Marek Kovar, Ondrej Stepanek. Trends Immunol. 2023 Nov;44(11):890-901.
doi: 10.1016/j.it.2023.09.003. PMID: 37827864; PMCID: PMC7615502.
Antifouling Properties of Poly(2-Oxazoline)s and Poly(2-Oxazine)s: Direct Comparison of Polymer-Coated Surfaces with the Same Coating Parameters. Jan Svoboda, Niccolo Lusiani, Radoslava Sivkova, Ognen Pop-Georgievski, Ondrej Sedlacek. Macromol Rapid Commun. 2023 Sep;44(17):e2300168.
doi: 10.1002/marc.202300168. PMID: 37220400.
Hydrophilic Copolymers with Hydroxamic Acid Groups as a Protective Biocompatible Coating of Maghemite Nanoparticles: Synthesis, Physico-Chemical Characterization and MRI Biodistribution Study. Hana Charvátová, Zdeněk Plichta, Jiřina Hromádková, Vít Herynek, Michal Babič. Pharmaceutics. 2023 Jul 19;15(7):1982.
doi: 10.3390/pharmaceutics15071982. PMID: 37514168; PMCID: PMC10384990.
Polyelectrolyte nanoparticles based on poly[N-(2-hydroxypropyl)methacrylamide-block-poly(N-(3-aminopropyl)methacrylamide] copolymers for delivery of heparin-binding proteins. Gabriela S. García-Briones, Richard Laga, Zulfiya Černochová, Carely Arjona-Ruiz, Olga Janoušková, Miroslav Šlouf, Ognen Pop-Georgievski, Dana Kubies. European Polymer Journal, Volume 191, 2023, 111976, ISSN 0014-3057.
doi: 10.1016/j.eurpolymj.2023.111976.
Singlet Oxygen In Vivo: It Is All about Intensity-Part 2. Steffen Hackbarth, Shanghui Gao, Vladimír Šubr, Lisheng Lin, Jakob Pohl, Tomáš Etrych, Jun Fang. J Pers Med. 2023 Apr 30;13(5):781.
doi: 10.3390/jpm13050781. PMID: 37240951; PMCID: PMC10222680.
Adaptable polymerization platform for therapeutics with tunable biodegradability. Hrochová M, Kotrchová L, Frejková M, Konefał R, Gao S, Fang J, Kostka L, Etrych T. Acta Biomater. 2023 Nov;171:417-427.
doi: 10.1016/j.actbio.2023.09.004. PMID: 37696413.
Stimuli-Responsive Polymer Nanoprobes Intended for Fluorescence-Guided Surgery of Malignant Head-and-Neck Tumors and Metastases. Robert Pola, Eliška Grosmanová, Michal Pechar, Dominik Horák, Tereza Krunclová, Jan Pankrác, Maxime Henry, Martin Kaňa, Jan Bouček, Luděk Šefc, Jean-Luc Coll, Tomáš Etrych. Adv Healthc Mater. 2023 Nov;12(28):e2301183.
doi: 10.1002/adhm.202301183. PMID: 37288946.
Polymer theranostics with multiple stimuli-based activation of photodynamic therapy and tumor imaging. Marina Rodrigues Tavares, Rayhanul Islam, Vladimír Šubr, Steffen Hackbarth, Shanghui Gao, Kai Yang, Volodymyr Lobaz, Jun Fang, Tomáš Etrych. Theranostics. 2023 Sep 4;13(14):4952-4973.
doi: 10.7150/thno.86211. PMID: 37771769; PMCID: PMC10526675.
The PANcreatic Disease ReseArch (PANDoRA) consortium: Ten years' experience of association studies to understand the genetic architecture of pancreatic cancer. Daniele Campa, Manuel Gentiluomo, Angelika Stein, Mateus Nóbrega Aoki, Martin Oliverius, Ludmila Vodičková, Krzysztof Jamroziak, George Theodoropoulos, Claudio Pasquali, William Greenhalf, Paolo Giorgio Arcidiacono, Faik Uzunoglu, Raffaele Pezzilli, Claudio Luchini, Marta Puzzono, Martin Loos, Matteo Giaccherini, Verena Katzke, Andrea Mambrini, Edita Kiudeliene, Kauffmann Emanuele Federico, Julia Johansen, Tamás Hussein, Beatrice Mohelnikova-Duchonova, Casper H J van Eijck, Hermann Brenner, Riccardo Farinella, Juan Sainz Pérez, Martin Lovecek, Markus W Büchler, Viktor Hlavac, Jakob R Izbicki, Thilo Hackert, Roger Chammas, Alessandro Zerbi, Rita Lawlor, Alessio Felici, Mara Götz, Gabriele Capurso, Laura Ginocchi, Maria Gazouli, Juozas Kupcinskas, Giulia Martina Cavestro, Pavel Vodicka, Stefania Moz, John P Neoptolemos, Lumir Kunovsky, Stig E Bojesen, Silvia Carrara, Domenica Gioffreda, Egidijus Morkunas, Olga Abian, Stefania Bunduc, Daniela Basso, Ugo Boggi, Barbara Wlodarczyk, Andrea Szentesi, Giuseppe Vanella, Inna Chen, Maarten F Bijlsma, Vytautas Kiudelis, Stefano Landi, Ben Schöttker, Chiara Corradi, Nathalia Giese, Rudolf Kaaks, Giulia Peduzzi, Péter Hegyi, Luca Morelli, Niccolò Furbetta, Pavel Soucek, Anna Latiano, Renata Talar-Wojnarowska, Sidsel C Lindgaard, Frederike Dijk, Anna Caterina Milanetto, Francesca Tavano, Klara Cervena, Bálint Erőss, Sabrina G Testoni, Judith H E Verhagen-Oldenampsen, Ewa Małecka-Wojciesko, Eithne Costello, Roberto Salvia, Evaristo Maiello, Stefano Ermini, Cosimo Sperti, Bernd Holleczek, Francesco Perri, Jurgita Skieceviciene, Livia Archibugi, Maurizio Lucchesi, Cosmeri Rizzato, Federico Canzian. Crit Rev Oncol Hematol. 2023 Jun;186:104020.
doi: 10.1016/j.critrevonc.2023.104020. PMID: 37164172.
Mitochondrially targeted tamoxifen in patients with metastatic solid tumours: an open-label, phase I/Ib single-centre trial. Zuzana Bielcikova, Jan Stursa, Ludmila Krizova, Lanfeng Dong, Jan Spacek, Stanislav Hlousek, Michal Vocka, Katerina Rohlenova, Olga Bartosova, Vladimir Cerny, Tomas Padrta, Michal Pesta, Pavel Michalek, Sona Stemberkova Hubackova, Katarina Kolostova, Eliska Pospisilova, Vladimir Bobek, Peter Klezl, Renata Zobalova, Berwini Endaya, Jakub Rohlena, Lubos Petruzelka, Lukas Werner, Jiri Neuzil. EClinicalMedicine. 2023 Feb 23;57:101873.
doi: 10.1016/j.eclinm.2023.101873. PMID: 37064512; PMCID: PMC10102891.
Targeting Prostate Cancer Using Bispecific T-Cell Engagers against Prostate-Specific Membrane Antigen. Gargi Das, Jakub Ptacek, Barbora Havlinova, Jana Nedvedova, Cyril Barinka, Zora Novakova. ACS Pharmacol Transl Sci. 2023 Oct 6;6(11):1703-1714.
doi: 10.1021/acsptsci.3c00159. PMID: 37974624.
Frentizole derivatives with mTOR inhibiting and senomorphic properties. Zofia Chrienova, David Rysanek, Josef Novak, Pavla Vasicova, Patrik Oleksak, Rudolf Andrys, Adam Skarka, Jelena Dumanovic, Zoran Milovanovic, Vesna Jacevic, Marketa Chvojkova, Kristina Holubova, Karel Vales, Veronika Skoupilova, Marian Valko, Klaudia Jomova, Suliman Y Alomar, Fernanda D Botelho, Tanos C C Franca, Kamil Kuca, Zdenek Hodny, Eugenie Nepovimova. Biomed Pharmacother. 2023 Nov;167:115600.
doi: 10.1016/j.biopha.2023.115600. PMID: 37783152.
Terminal differentiation of villus tip enterocytes is governed by distinct Tgfβ superfamily members. Linda Berková, Hassan Fazilaty, Qiutan Yang, Jan Kubovčiak, Monika Stastna, Dusan Hrckulak, Martina Vojtechova, Tosca Dalessi, Michael David Brügger, George Hausmann, Prisca Liberali, Vladimir Korinek, Konrad Basler, Tomas Valenta. EMBO Rep. 2023 Sep 6;24(9):e56454.
doi: 10.15252/embr.202256454. PMID: 37493498; PMCID: PMC10481656.
Ppm1d truncating mutations promote the development of genotoxic stress-induced AML. Monika Burocziova, Petr Danek, Anna Oravetzova, Zuzana Chalupova, Meritxell Alberich-Jorda, Libor Macurek. Leukemia. 2023 Nov;37(11):2209-2220.
doi: 10.1038/s41375-023-02030-8. PMID: 37709843; PMCID: PMC10624630.
ENIGMA CHEK2gether Project: A Comprehensive Study Identifies Functionally Impaired CHEK2 Germline Missense Variants Associated with Increased Breast Cancer Risk. Lenka Stolarova, Petra Kleiblova, Petra Zemankova, Barbora Stastna, Marketa Janatova, Jana Soukupova, Maria Isabel Achatz, Christine Ambrosone, Paraskevi Apostolou, Banu K Arun, Paul Auer, Mollie Barnard, Birgitte Bertelsen; Biobank Japan; Marinus J Blok, Nicholas Boddicker, Joan Brunet, Elizabeth S Burnside, Mariarosaria Calvello, Ian Campbell, Sock Hoai Chan, Fei Chen, Jian Bang Chiang, Anna Coppa, Laura Cortesi, Ana Crujeiras-González; Consortium CZECANCA; Kim De Leeneer, Robin De Putter, Allison DePersia, Lisa Devereux, Susan Domchek, Anna Efremidis, Christoph Engel, Corinna Ernst, D Gareth R Evans, Lidia Feliubadaló, Florentia Fostira, Olivia Fuentes-Ríos, Encarna B Gómez-García, Sara González, Christopher Haiman, Thomas van Overeem Hansen, Jan Hauke, James Hodge, Chunling Hu, Hongyan Huang, Nur Diana Binte Ishak, Yusuke Iwasaki, Irene Konstantopoulou, Peter Kraft, James Lacey, Conxi Lázaro, Na Li, Weng Khong Lim, Sara Lindstrom, Adriana Lori, Elana Martinez, Alexandra Martins, Koichi Matsuda, Giuseppe Matullo, Simone McInerny, Kyriaki Michailidou, Marco Montagna, Alvaro N A Monteiro, Luigi Mori, Katherine Nathanson, Susan L Neuhausen, Heli Nevanlinna, Janet E Olson, Julie Palmer, Barbara Pasini, Alpa Patel, Maria Piane, Bruce Poppe, Paolo Radice, Alessandra Renieri, Nicoletta Resta, Marcy E Richardson, Toon Rosseel, Kathryn J Ruddy, Marta Santamariña, Elizabeth Santana Dos Santos, Lauren Teras, Amanda E Toland, Amy Trentham-Dietz, Celine M Vachon, Alexander E Volk, Nana Weber-Lassalle, Jeffrey N Weitzel, Lisa Wiesmuller, Stacey Winham, Siddhartha Yadav, Drakoulis Yannoukakos, Song Yao, Valentina Zampiga, Magnus Zethoven, Ze Wen Zhang, Tomas Zima, Amanda B Spurdle, Ana Vega, Maria Rossing, Jesús Del Valle, Arcangela De Nicolo, Eric Hahnen, Kathleen B M Claes, Joanne Ngeow, Yukihide Momozawa, Paul A James, Fergus J Couch, Libor Macurek, Zdenek Kleibl. Clin Cancer Res. 2023 Aug 15;29(16):3037-3050.
doi: 10.1158/1078-0432.CCR-23-0212. PMID: 37449874; PMCID: PMC10425727.
Chronic inflammation promotes cancer progression as a second hit. Monika Burocziova, Srdjan Grusanovic, Karolina Vanickova, Sladjana Kosanovic, Meritxell Alberich-Jorda. Exp Hematol. 2023 Dec;128:30-37.
doi: 10.1016/j.exphem.2023.09.002. PMID: 37709251.
Hematopoietic stem cells undergo a lymphoid to myeloid switch in early stages of emergency granulopoiesis. Karolina Vanickova, Mirko Milosevic, Irina Ribeiro Bas, Monika Burocziova, Asumi Yokota, Petr Danek, Srdjan Grusanovic, Mateusz Chiliński, Dariusz Plewczynski, Jakub Rohlena, Hideyo Hirai, Katerina Rohlenova, Meritxell Alberich-Jorda. EMBO J. 2023 Dec 1;42(23):e113527.
doi: 10.15252/embj.2023113527. PMID: 37846891; PMCID: PMC10690458.
Discovery of tert-Butyl Ester Based 6-Diazo-5-oxo-l-norleucine Prodrugs for Enhanced Metabolic Stability and Tumor Delivery. Kateřina Novotná, Lukáš Tenora, Eva Prchalová, James Paule, Jesse Alt, Vijay Veeravalli, Jenny Lam, Ying Wu, Ivan Šnajdr, Sadakatali Gori, Vijaya Saradhi Mettu, Takashi Tsukamoto, Pavel Majer, Barbara S Slusher, Rana Rais. J Med Chem. 2023 Nov 23;66(22):15493-15510.
doi: 10.1021/acs.jmedchem.3c01681. PMID: 37949450; PMCID: PMC10683027.
Randomizing for Alzheimer's disease drug trials should consider the cancer history of participants. Viswanath Das, Marián Hajdúch. Brain. 2023 Oct 3;146(10):e75-e76.
doi: 10.1093/brain/awad177. PMID: 37243427.
Drug-Drug Interactions of Cannabidiol with Standard-of-Care Chemotherapeutics. Tereza Buchtova, David Lukac, Zdenek Skrott, Katarina Chroma, Jiri Bartek, Martin Mistrik. Int J Mol Sci. 2023 Feb 2;24(3):2885.
doi: 10.3390/ijms24032885. PMID: 36769206; PMCID: PMC9917508.
Increased blood reactive oxygen species and hepcidin in obstructive sleep apnea precludes expected erythrocytosis. Jihyun Song, Krishna M Sundar, Monika Horvathova, Radhika Gangaraju, Karel Indrak, Robert D Christensen, Samuel Genzor, Carsten Lundby, Vladimir Divoky, Tomas Ganz, Josef T Prchal. Am J Hematol. 2023 Aug;98(8):1265-1276.
doi: 10.1002/ajh.26992. PMID: 37350302.
2,4-Diaryl-pyrimido[1,2-a]benzimidazole derivatives as novel anticancer agents endowed with potent anti-leukemia activity: Synthesis, biological evaluation and kinase profiling. Moataz A Shaldam, Denisa Hendrychová, Radwan El-Haggar, Veronika Vojáčková, Taghreed A Majrashi, Eslam B Elkaeed, Nicolas Masurier, Vladimír Kryštof, Haytham O Tawfik, Wagdy M Eldehna. Eur J Med Chem. 2023 Oct 5;258:115610.
doi: 10.1016/j.ejmech.2023.115610. PMID: 37437350.
A unique case of AH-dominant type nodular pulmonary amyloidosis presenting as a spontaneous pneumothorax: a case report and review of the literature. Valeria Skopelidou, Pavel Hurník, Lubomír Tulinský, Vladimir Židlík, Jiří Lenz, Patricie Delongová, Helena Hornychová, Patrik Flodr, Tomáš Jelínek, Ludmila Muroňová, Dušan Holub, Petr Džubák, Marián Hajdúch. Pathol Oncol Res. 2023 Sep 22;29:1611390.
doi: 10.3389/pore.2023.1611390. PMID: 37808084; PMCID: PMC10556250.
Circulating tumor cell-derived preclinical models: current status and future perspectives. Zuzana Kahounová, Markéta Pícková, Stanislav Drápela, Jan Bouchal, Eva Szczyrbová, Jiří Navrátil, Karel Souček. Cell Death Dis. 2023 Aug 17;14(8):530.
doi: 10.1038/s41419-023-06059-6. PMID: 37591867; PMCID: PMC10435501.
Discrimination of resected glioma tissues using surface enhanced Raman spectroscopy and Au@ZrO2 plasmonic nanosensor. Vaclav Ranc, Ondrej Pavlacka, Ondrej Kalita, Miroslav Vaverka. Spectrochim Acta A Mol Biomol Spectrosc. 2024 Jan 15;305:123521.
doi: 10.1016/j.saa.2023.123521. PMID: 37862838.
Nucleoside-based anticancer drugs: Mechanism of action and drug resistance. Lenka Hruba, Viswanath Das, Marian Hajduch, Petr Dzubak. Biochem Pharmacol. 2023 Sep;215:115741.
doi: 10.1016/j.bcp.2023.115741. PMID: 37567317.
Pathogenesis of Alzheimer's disease: Involvement of the choroid plexus. Maria Čarna, Isaac G Onyango, Stanislav Katina, Dušan Holub, Jan Sebastian Novotny, Marketa Nezvedova, Durga Jha, Zuzana Nedelska, Valentina Lacovich, Thijs Vande Vyvere, Ruben Houbrechts, Krystine Garcia-Mansfield, Ritin Sharma, Victoria David-Dirgo, Martin Vyhnalek, Kateřina Texlova, Hernan Chaves, Nadine Bakkar, Lucia Pertierra, Mojmir Vinkler, Hana Markova, Jan Laczo, Kateřina Sheardova, Marcela Hortova-Kohoutkova, Jan Frič, Giancarlo Forte, Petr Kaňovsky, Silvie Belaškova, Jiři Damborsky, Jakub Hort, Nicholas T Seyfried, Robert Bowser, Gustavo Sevlever, Robert A Rissman, Richard A Smith, Marian Hajduch, Patrick Pirrotte, Zdenek Spacil, Eric B Dammer, Clara Limbäck-Stokin, Gorazd B Stokin. Alzheimers Dement. 2023 Aug;19(8):3537-3554.
doi: 10.1002/alz.12970. PMID: 36825691.
More Than 2% of Circulating Tumor Plasma Cells Defines Plasma Cell Leukemia-Like Multiple Myeloma. Tomas Jelinek, Renata Bezdekova, David Zihala, Tereza Sevcikova, Anjana Anilkumar Sithara, Lenka Pospisilova, Sabina Sevcikova, Petra Polackova, Martin Stork, Zdenka Knechtova, Ondrej Venglar, Veronika Kapustova, Tereza Popkova, Ludmila Muronova, Zuzana Chyra, Matous Hrdinka, Michal Simicek, Juan-Jose Garcés, Noemi Puig, Maria-Teresa Cedena, Artur Jurczyszyn, Jorge J Castillo, Miroslav Penka, Jakub Radocha, Maria Victoria Mateos, Jesús F San-Miguel, Bruno Paiva, Ludek Pour, Lucie Rihova, Roman Hajek. J Clin Oncol. 2023 Mar 1;41(7):1383-1392.
doi: 10.1200/JCO.22.01226. PMID: 36315921; PMCID: PMC9995102.
From fish to cells: Establishment of continuous cell lines from embryos of annual killifish Nothobranchius furzeri and N. kadleci. Kamila Součková, Matej Jasík, Iva Sovadinová, Alexandr Sember, Eliška Sychrová, Anna Konieczna, Vojtěch Bystrý, Iva Dyková, Radim Blažek, Karolína Lukšíková, Tomáš Pavlica, Marek Jankásek, Marie Altmanová, Jakub Žák, Adriana Zbončáková, Martin Reichard, Ondřej Slabý. Aquat Toxicol. 2023 Jun;259:106517.
doi: 10.1016/j.aquatox.2023.106517. PMID: 37087860.
Gemtuzumab ozogamicin plus midostaurin in conjunction with standard intensive therapy for FLT3- mutated acute myeloid leukemia patients - Czech center experience. Barbora Weinbergerová, Martin Čerňan, Tomáš Kabut, Lukáš Semerád, Natália Podstavková, Tomáš Szotkowski, Ivana Ježíšková, Jiří Mayer. Haematologica. 2023 Oct 1;108(10):2826-2829.
doi: 10.3324/haematol.2022.282263. PMID: 36815379; PMCID: PMC10542832.
Targeted treatment of severe vascular malformations harboring PIK3CA and TEK mutations with alpelisib is highly effective with limited toxicity. Martin Sterba, Petra Pokorna, Renata Faberova, Blanka Pinkova, Jarmila Skotakova, Anna Seehofnerova, Jan Blatny, Lucia Janigova, Olga Koskova, Hana Palova, Michal Mahdal, Lukas Pazourek, Petr Jabandziev, Ondrej Slaby, Peter Mudry, Jaroslav Sterba. Sci Rep. 2023 Jun 28;13(1):10499.
doi: 10.1038/s41598-023-37468-4. PMID: 37380669; PMCID: PMC10307862.
Desmocollin-1 is associated with pro-metastatic phenotype of luminal A breast cancer cells and is modulated by parthenolide. Petr Lapcik, Petr Sulc, Lucia Janacova, Katerina Jilkova, David Potesil, Pavla Bouchalova, Petr Müller, Pavel Bouchal Cell Mol Biol Lett. 2023 Aug 24;28(1):68.
doi: 10.1186/s11658-023-00481-6. PMID: 37620794; PMCID: PMC10464112.
Electrochemical biosensors for analysis of DNA point mutations in cancer research. Katerina Ondraskova, Ravery Sebuyoya, Ludmila Moranova, Jitka Holcakova, Petr Vonka, Roman Hrstka, Martin Bartosik. Anal Bioanal Chem. 2023 Mar;415(6):1065-1085.
doi: 10.1007/s00216-022-04388-7. PMID: 36289102.
Expression dynamics of metalloproteinases during mandibular bone formation: association with Myb transcription factor. Varadinkova S, Oralova V, Clarke M, Frampton J, Knopfova L, Lesot H, Bartos P, Matalova E. Front Cell Dev Biol. 2023 Aug 28;11:1168866.
doi: 10.3389/fcell.2023.1168866. PMID: 37701782; PMCID: PMC10493412.
In-depth analysis of biocatalysts by microfluidics: An emerging source of data for machine learning. Michal Vasina, David Kovar, Jiri Damborsky, Yun Ding, Tianjin Yang, Andrew deMello, Stanislav Mazurenko, Stavros Stavrakis, Zbynek Prokop. Biotechnol Adv. 2023 Sep;66:108171.
doi: 10.1016/j.biotechadv.2023.108171. PMID: 37150331.
Lysin (K)-specific demethylase 1 inhibition enhances proteasome inhibitor response and overcomes drug resistance in multiple myeloma. Cecilia Bandini, Elisabetta Mereu, Tina Paradzik, Maria Labrador, Monica Maccagno, Michela Cumerlato, Federico Oreglia, Lorenzo Prever, Veronica Manicardi, Elisa Taiana, Domenica Ronchetti, Mattia D'Agostino, Francesca Gay, Alessandra Larocca, Lenka Besse, Giorgio Roberto Merlo, Emilio Hirsch, Alessia Ciarrocchi, Giorgio Inghirami, Antonino Neri, Roberto Piva. Exp Hematol Oncol. 2023 Aug 10;12(1):71.
doi: 10.1186/s40164-023-00434-x. PMID: 37563685; PMCID: PMC10413620.
Optimized procedure for high-throughput transcriptome profiling of small extracellular vesicles isolated from low volume serum samples. Petra Vychytilova-Faltejskova, Sara Vilmanova, Lucie Pifkova, Tina Catela Ivković, Marie Mᶏdrzyk, Robin Jugas, Tana Machackova, Jan Kotoucek, Milana Sachlova, Lucia Bohovicova, Teodor Stanek, Jana Halamkova, Igor Kiss, Ondrej Slaby. Clin Chem Lab Med. 2023 Jul 31;62(1):157-167.
doi: 10.1515/cclm-2023-0610. PMID: 37505924.
pyCaverDock: Python implementation of the popular tool for analysis of ligand transport with advanced caching and batch calculation support. Ondrej Vavra, Jakub Beranek, Jan Stourac, Martin Surkovsky, Jiri Filipovic , Jiri Damborsky, Jan Martinovic, David Bednar. Bioinformatics. 2023 Aug 1;39(8):btad443.
doi: 10.1093/bioinformatics/btad443. PMID: 37471591; PMCID: PMC10397418.
SBILib: a handle for protein modeling and engineering. Patrick Gohl, Jaume Bonet, Oriol Fornes, Joan Planas-Iglesias, Narcís Fernandez-Fuentes, Baldo Oliva. Bioinformatics. 2023 Oct 3;39(10):btad613.
doi: 10.1093/bioinformatics/btad613. PMID: 37796837; PMCID: PMC10589914.
Tumor Cell-Intrinsic c-Myb Upregulation Stimulates Antitumor Immunity in a Murine Colorectal Cancer Model. Merel van Gogh, Jesus F Glaus Garzon, Dilara Sahin, Lucia Knopfova, Petr Benes, Onur Boyman, Igor Jurisica, Lubor Borsig. Cancer Immunol Res. 2023 Oct 4;11(10):1432-1444.
doi: 10.1158/2326-6066.CIR-22-0912. PMID: 37478172; PMCID: PMC10548106.
Molecular portraits of colorectal cancer morphological regions. Eva Budinská, Martina Hrivňáková, Tina Catela Ivkovic, Marie Madrzyk, Rudolf Nenutil, Beatrix Bencsiková, Dagmar Al Tukmachi, Michaela Ručková, Lenka Zdražilová Dubská, Ondřej Slabý, Josef Feit, Mihnea-Paul Dragomir, Petra Borilova Linhartova, Sabine Tejpar, Vlad Popovici. Elife. 2023 Nov 13;12:RP86655.
doi: 10.7554/eLife.86655. PMID: 37956043; PMCID: PMC10642970.
MiR-4649-5p acts as a tumor-suppressive microRNA in triple negative breast cancer by direct interaction with PIP5K1C, thereby potentiating growth-inhibitory effects of the AKT inhibitor capivasertib. Katharina Jonas, Felix Prinz, Manuela Ferracin, Katarina Krajina, Barbara Pasculli, Alexander Deutsch, Tobias Madl, Beate Rinner, Ondrej Slaby, Christiane Klec, Martin Pichler. Breast Cancer Res. 2023 Oct 6;25(1):119.
doi: 10.1186/s13058-023-01716-2. PMID: 37803350; PMCID: PMC10559525.
Disclosing quantitative RT-PCR raw data during manuscript submission: a call for action. Andreas Untergasser, Jan Hellemans, Michael W Pfaffl, Jan M Ruijter, Maurice J B van den Hoff, Mihnea P Dragomir, Douglas Adamoski, Sandra Martha Gomes Dias, Rui Manuel Reis, Manuela Ferracin, Emmanuel Dias-Neto, Ian Marsh, Mikael Kubista, Muller Fabbri, Ajay Goel, Ondřej Slabý, Erik Knutsen, Baoqing Chen, Massimo Negrini, Koshi Mimori, Martin Pichler, Maria Papatriantafyllou, Simone Anfossi, Thomas D Schmittgen, Jim Huggett, Stephen Bustin, Jo Vandesompele, George A Calin; HEROIC (tHe initiativE gRoup On qRT dIsClosure) Consortium. Mol Oncol. 2023 May;17(5):713-717.
doi: 10.1002/1878-0261.13418. PMID: 36916500; PMCID: PMC10158759.
Intestinal Paneth cell differentiation relies on asymmetric regulation of Wnt signaling by Daam1/2. Gabriele Colozza, Heetak Lee, Alessandra Merenda, Szu-Hsien Sam Wu, Andrea Català-Bordes, Tomasz W Radaszkiewicz, Ingrid Jordens, Ji-Hyun Lee, Aileen-Diane Bamford, Fiona Farnhammer, Teck Yew Low, Madelon M Maurice, Vítězslav Bryja, Jihoon Kim, Bon-Kyoung Koo. Sci Adv. 2023 Nov 24;9(47):eadh9673.
doi: 10.1126/sciadv.adh9673. PMID: 38000028; PMCID: PMC10672176.
Spatiotemporal monitoring of hard tissue development reveals unknown features of tooth and bone development. Marcos Gonzalez Lopez, Barbora Huteckova, Josef Lavicky, Nikodem Zezula, Vladislav Rakultsev, Vendula Fridrichova, Haneen Tuaima, Cita Nottmeier, Julian Petersen, Michaela Kavkova, Tomas Zikmund, Jozef Kaiser, Rupali Lav, Haza Star, Vítězslav Bryja, Petr Henyš, Miroslav Vořechovský, Abigail S Tucker, Jakub Harnos, Marcela Buchtova, Jan Krivanek. Sci Adv. 2023 Aug 2;9(31):eadi0482.
doi: 10.1126/sciadv.adi0482. PMID: 37531427; PMCID: PMC10396306.
High-dose aciclovir in CMV infection prophylaxis after allogeneic HSCT: a single-center long-term experience. Tomáš Kabut, Barbora Weinbergerová, František Folber, Martina Lengerová, Jiří Mayer. Bone Marrow Transplant. 2023 Nov;58(11):1229-1236.
doi: 10.1038/s41409-023-02081-6. PMID: 37612466; PMCID: PMC10622319.
Different prognostic impact of recurrent gene mutations in chronic lymphocytic leukemia depending on IGHV gene somatic hypermutation status: a study by ERIC in HARMONY. Larry Mansouri, Birna Thorvaldsdottir, Lesley-Ann Sutton, Georgios Karakatsoulis, Manja Meggendorfer, Helen Parker, Ferran Nadeu, Christian Brieghel, Stamatia Laidou, Riccardo Moia, Davide Rossi, Mark Catherwood, Jana Kotaskova, Julio Delgado, Ana E Rodríguez-Vicente, Rocío Benito, Gian Matteo Rigolin, Silvia Bonfiglio, Lydia Scarfo, Mattias Mattsson, Zadie Davis, Ajay Gogia, Lata Rani, Panagiotis Baliakas, Hassan Foroughi-Asl, Cecilia Jylhä, Aron Skaftason, Inmaculada Rapado, Fatima Miras, Joaquín Martinez-Lopez, Javier de la Serna, Jesús María Hernández Rivas, Patrick Thornton, María José Larráyoz, María José Calasanz, Viktória Fésüs, Zoltán Mátrai, Csaba Bödör, Karin E Smedby, Blanca Espinet, Anna Puiggros, Ritu Gupta, Lars Bullinger, Francesc Bosch, Bárbara Tazón-Vega, Fanny Baran-Marszak, David Oscier, Florence Nguyen-Khac, Thorsten Zenz, Maria Jose Terol, Antonio Cuneo, María Hernández-Sánchez, Sarka Pospisilova, Ken Mills, Gianluca Gaidano, Carsten U Niemann, Elias Campo, Jonathan C Strefford, Paolo Ghia, Kostas Stamatopoulos, Richard Rosenquist. Leukemia. 2023 Feb;37(2):339-347.
doi: 10.1038/s41375-022-01802-y. PMID: 36566271; PMCID: PMC9898037.
Infrared Laser Desorption of Intact Nanoparticles for Digital Tissue Imaging. Marek Stiborek, Lenka Jindřichová, Stanislava Meliorisová, Antonín Bednařík, Vadym Prysiazhnyi, Jiří Kroupa, Pavel Houška, Barbora Adamová, Jarmila Navrátilová, Viktor Kanický, Jan Preisler. Anal Chem. 2022 Dec 27;94(51):18114-18120.
doi: 10.1021/acs.analchem.2c05216. PMID: 36514811.
Serum concentrations of proinflammatory biomarker interleukin-6 (IL-6) as a predictor of postoperative complications after elective colorectal surgery. Vladimír Procházka, Lukáš Lacina, Karel Smetana Jr, Martin Svoboda, Kateřina Skřivanová, Miroslava Beňovská, Jiří Jarkovský, Leoš Křen, Zdeněk Kala. World J Surg Oncol. 2023 Dec 14;21(1):384.
doi: 10.1186/s12957-023-03270-9. PMID: 38098074; PMCID: PMC10720211.
Molecular interactions of adaptor protein PSTPIP2 control neutrophil-mediated responses leading to autoinflammation. Nataliia Pavliuchenko, Iris Duric, Jarmila Kralova, Matej Fabisik, Frantisek Spoutil, Jan Prochazka, Petr Kasparek, Jana Pokorna, Tereza Skopcova, Radislav Sedlacek, Tomas Brdicka. Front Immunol. 2022 Dec 20;13:1035226.
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A patent review of cyclin-dependent kinase 7 (CDK7) inhibitors (2018-2022). Marketa Kovalová, Joseph Peter Baraka, Václav Mik, Radek Jorda, Lei Luo, Hao Shao, Vladimír Kryštof. Expert Opin Ther Pat. 2023 Feb;33(2):67-87.
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Active eosinophils regulate host defence and immune responses in colitis. Alessandra Gurtner, Costanza Borrelli, Ignacio Gonzalez-Perez, Karsten Bach, Ilhan E Acar, Nicolás G Núñez, Daniel Crepaz, Kristina Handler, Vivian P Vu, Atefeh Lafzi, Kristin Stirm, Deeksha Raju, Julia Gschwend, Konrad Basler, Christoph Schneider, Emma Slack, Tomas Valenta, Burkhard Becher, Philippe Krebs, Andreas E Moor, Isabelle C Arnold. Nature 2023, 615(7950):151-157.
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AMACR Expression is a Potential Diagnostic Marker in Apocrine Lesions of Breast, and is Associated with High Histologic Grade and Lymph Node Metastases in Some Invasive Apocrine Breast Cancers. Gabriel Lerner, Haiming Tang, Kamaljeet Singh, Reza Golestani, Samantha St Claire, Peter A Humphrey, Donald Lannin, Radoslav Janostiak, Malini Harigopal. Clin Breast Cancer. 2023 Feb;23(2):199-210.
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A-ring-fused pyrazoles of dihydrotestosterone targeting prostate cancer cells via the downregulation of the androgen receptor. Miroslav Peřina, Márton A Kiss, Gergo Motoyán, Eva Szczyrbová, Martin Eliáš, Vladimír Študent Jr, Daniela Kurfurstová, Markéta Kovalová, Lukáš Mada, Jan Bouchal, Eva Frank, Radek Jorda. Eur J Med Chem. 2023 Mar 5;249:115086.
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Cannabis-derived products antagonize platinum drugs by altered cellular transport. Tereza Buchtová, Lucie Beresova, Katarina Chromá, Tomáš Pluhacek, Tibor Beres, Dominika Kaczorova, Petr Tarkowski, Jiri Bartek, Martin Mistrík. Biomed Pharmacother. 2023 May 1;163:114801.
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Circulating tumor nucleic acids: biology, release mechanisms, and clinical relevance. Pavel Stejskal, Hani Goodarzi, Josef Srovnal, Marián Hajdúch, Laura J vant Veer, Mark Jesus M Magbanua. Mol Cancer. 2023 Jan 21;22(1):15.
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Clinical lipidomics in the era of the big data. Aleš Kvasnička, Lukáš Najdekr, Dana Dobešová, Barbora Piskláková, Eliška Ivanovová, David Friedecký. Clin Chem Lab Med. 2023 Jan 4;61(4):587-598.
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Clonal origin and development of high hyperdiploidy in childhood acute lymphoblastic leukaemia. Eleanor L Woodward, Minjun Yang, Larissa H Moura-Castro, Hilda van den Bos, Rebeqa Gunnarsson Linda Olsson-Arvidsson, Diana C J Spierings, Anders Castor, Nicolas Duployez, Marketa Zaliova, Jan Zuna, Bertil Johansson, Floris Foijer, Kajsa Paulsson. Nat Commun. 2023 Mar 25;14(1):1658.
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Constitutively active Lyn kinase causes a cutaneous small vessel vasculitis and liver fibrosis syndrome. Adriana A de Jesus, Guibin Chen, Dan Yang, Tomas Brdicka, Natasha M Ruth, David Bennin, Dita Cebecauerova, Hana Malcova, Helen Freeman, Neil Martin, Karel Svojgr, Murray H Passo, Farzana Bhuyan, Sara Alehashemi, Andre T Rastegar, Katsiaryna Uss, Lela Kardava, Bernadette Marrero, Iris Duric, Ebun Omoyinmi, Petra Peldova, Chyi-Chia Richard Lee, David E Kleiner, Colleen M Hadigan, Stephen M Hewitt, Stefania Pittaluga, Carmelo Carmona-Rivera, Katherine R Calvo, Nirali Shah, Miroslava Balascakova, Danielle L Fink, Radana Kotalova, Zuzana Parackova, Lucie Peterkova, Daniela Kuzilkova, Vit Campr, Lucie Sramkova, Angelique Biancotto, Stephen R Brooks, Cameron Manes, Eric Meffre, Rebecca L Harper, Hyesun Kuehn, Mariana J Kaplan, Paul Brogan, Sergio D Rosenzweig, Melinda Merchant, Zuoming Deng, Anna Huttenlocher, Susan L Moir, Douglas B Kuhns, Manfred Boehm, Karolina Skvarova Kramarzova, Raphaela Goldbach-Mansky. Nat Commun. 2023 Mar 17;14(1):1502.
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Cytoplasmic Tail of MT1-MMP: A Hub of MT1-MMP Regulation and Function. Katerina Strouhalova, Ondřej Tolde, Daniel Rosel, Jan Brábek. Int J Mol Sci 2023 Mar 7;24(6):5068.
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Cytotoxicity evaluation of photosensitizer-conjugated hexagonal upconverting nanoparticles. Mykhailo Nahorniak, Viktoriia Oleksa, Taras Vasylyshyn, Ognen Pop-Georgievski, Eliška Rydvalová, Marcela Filipová, Daniel Horák. Nanomaterials 2023. Roč. 13, č. 9, č. článku 1535.
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Design, Synthesis, Biological Evaluation, and Crystallographic Study of Novel Purine Nucleoside Phosphorylase Inhibitors. Jan Skácel, Stefan Djukic, Ondřej Baszczyňski, Filip Kalčic, Tadeáš Bílek, Karel Chalupský, Jaroslav Kozák, Alexandra Dvořáková, Eva Tloušt’ová, Zuzana Král’ová, Markéta Šmídková, Jan Voldřich, Michaela Rumlová, Petr Pachl, Jiří Brynda, Tereza Vučková, Milan Fábry, Jan Snášel, Iva Pichová, Pavlína Řezáčová, Helena Mertlíková-Kaiserová, Zlatko Janeba. Journal of Medicinal Chemistry, 2023.
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DiaPASEF proteotype analysis indicates changes in cell growth and metabolic switch induced by caspase-9 inhibition in chondrogenic cells. Petr Lapcik, Barbora Vesela, David Potesil, Katerina Dadakova, Martina Zapletalova, Petr Benes, Pavel Bouchal, Eva Matalova. Proteomics, 00, e2200408.
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Engine shutdown: migrastatic strategies and prevention of metastases. Martina Raudenská, Kateřina Petrláková, Tamara Juriňáková, Jindřiška Leischner Fialová, Michaela Fojtů, Milan Jakubek, Daniel Rösel, Jan Brábek, Michal Masařík. Trends in Cancer 2023, 9(4), 293.
doi: 10.1016/j.trecan.2023.01.001. PMID: 36804341
Evaluation of linear versus star-like polymer anti-cancer nanomedicines in mouse models. Libor Kostka, Lenka Kotrchová, Eva Randárová, Carolina A. Ferreira, Iva Malátová, Hye Jin Lee, Aeli P. Olson, Jonathan W. Engle, Marek Kovář, Weibo Cai, Milada Šírová, Tomáš Etrych. Journal of Controlled Release. Roč. 353, January (2023), s. 549-562.
doi: 10.1016/j.jconrel.2022.11.060. PMID: 36470330
Expression of Selected miRNAs in Normal and Cancer-Associated Fibroblasts and in BxPc3 and MIA PaCa-2 Cell Lines of Pancreatic Ductal Adenocarcinoma. Václav Mandys, Alexey Popov, Robert Gürlich, Jan Havránek, Lucie Pfeiferová, Michal Kolář, Jana Vránová, Karel Smetana, Jr., Lukáš Lacina, Pavol Szabo. Int. J. Mol. Sci. 2023, 24(4), 3617.
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FoxP3 Expression in Tumor-Infiltrating Lymphocytes as Potential Predictor of Response to Immune Checkpoint Inhibitors in Patients with Advanced Melanoma and Non-Small Cell Lung Cancer. Peter Grell, Simona Borilova, Pavel Fabian, Iveta Selingerova, David Novak, Petr Muller, Igor Kiss, Rostislav Vyzula. Cancers 2023;15(6):1901.
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HPMA copolymer conjugated 5-aminolevulinic acid exhibits superior efficacy for photodynamic therapy with tumor-responsive and targeting properties. Rayhanul Islam, Kevin Kotalík, Vladimír Šubr, Shanghui Gao, Jian-Rong Zhou, Kazumi Yokomizo, Tomáš Etrych, Jun Fang. Nanomedicine: Nanotechnology, Biology and Medicine 2023. Roč. 48, č. článku 102636.
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Characterization of new highly selective pyrazolo[4,3-d]pyrimidine inhibitor of CDK7. Markéta Kovalová, Libor Havlíček, Stefan Djukic, Jana Škerlová, Miroslav Peřina, Tomáš Pospíšil, Eva Řezníčková, Pavlína Řezáčová, Radek Jorda, Vladimír Kryštof. Biomedicine & Pharmacotherapy, 2023, 161: 114492.
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Chromatin Remodeling Enzyme Snf2h Is Essential for Retinal Cell Proliferation and Photoreceptor Maintenance. Andrea Kuzelova, Naoko Dupacova, Barbora Antosova, Sweetu Susan Sunny, Zbynek Kozmik, Jr., Jan Paces, Arthur I. Skoultchi, Tomas Stopka, and Zbynek Kozmik. 2023. Cells 12, no. 7: 1035.
doi: 10.3390/cells12071035. PMID: 37048108; PMCID: PMC10093269
Identification of AGR2 Gene-Specific Expression Patterns Associated with Epithelial-Mesenchymal Transition. Andrea Martisova, Lucia Sommerova, Adam Krejci, Iveta Selingerova, Tamara Kolarova, Filip Zavadil Kokas, Milos Holanek, Jan Podhorec, Tomas Kazda, Roman Hrstka. Int J Mol Sci. 2022 Sep 16;23(18):10845.
doi: 10.3390/ijms231810845. PMID: 36142758; PMCID: PMC9504245
Importance of Germline and Somatic Alterations in Human MRE11, RAD50, and NBN Genes Coding for MRN Complex. Barbora Otahalova, Zuzana Volkova, Jana Soukupova, Petra Kleiblova, Marketa Janatova, Michal Vocka, Libor Macurek, Zdenek Kleibl. Int J Mol Sci. 2023;24(6):5612.
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Long-term survival trends in solid cancers in the Nordic countries marking timing of improvements. Kari Jussi Hemminki, Asta Försti, Václav Liška, Anna Kanerva, Otto Hemminki, Akseli Hemminki. International Journal of Cancer 2023 May 1;152(9):1837-1846.
doi: 10.1002/ijc.34416. PMID: 36571455
Low Frequency of Cancer-Predisposition Gene Mutations in Liver Transplant Candidates with Hepatocellular Carcinoma. Klara Horackova, Sona Frankova, Petra Zemankova, Petr Nehasil, Marta Cerna, Magdalena Neroldova, Barbora Otahalova, Jan Kral, Milena Hovhannisyan, Viktor Stranecky, Tomas Zima, Marketa Safarikova, Marta Kalousova, Jan Novotny, Jan Sperl, Marianna Borecka, Sandra Jelinkova, Michal Vocka, Marketa Janatova, Petra Kleiblova, Zdenek Kleibl, Milan Jirsa, Jana Soukupova. Cancers (Basel). 2023 Dec 29;15(1):201.
doi: 10.3390/cancers15010201. PMID: 36612198
MicroRNA Profiling of Self-Renewing Human Neural Stem Cells Reveals Novel Sets of Differentially Expressed microRNAs During Neural Differentiation In Vitro. Veronika Fedorová, Kateřina Amruz Černá, Jan Oppelt, Veronika Pospíšilová, Tomáš Bárta, Marek Mraz, Dáša Bohačiaková. Stem Cell Rev and Rep (2023).
doi: 10.1007/s12015-023-10524-2. PMID: 36918496
Molecular Design of 68Ga- and 89Zr-labeled Anticalin radioligands for PET-imaging of PSMA-positive tumors. Volker Morath, Corinna Brandt, Friedrich-Christian Deuschle, Claudia T. Mendler, Claudia T. Mendler, Birgit Blechert, Dominik Summer, Cyril Barinka, Clemens Decristoforo, Wolfgang A. Weber, Markus Schwaiger, Arne Skerra. Mol. Pharmaceutics 2023,20(5), 2490-2501.
doi: 10.1021/acs.molpharmaceut.2c01066. PMID: 37068305
Molecular design, synthesis and anticancer activity of new thiopyrano[2,3-d]thiazoles based on 5-hydroxy-1,4-naphthoquinone (juglone). Iryna Ivasechko, Andrii Lozynskyi, Julia Senkiv, Piotr Roszczecko, Yuliia Kozak, Nataliya Finiuk, Olga Kluyuchivka, Nataliya Kashchak, Nazar Manko, Zvenyslava Maslyak, Daylo Lesyk, Andriy Karkhut, Svyatoslav Polovkovych, Robert Czarnomysy, Olga Szewczyk, Andriy Kozytskiy, Olexandr Karpenko, Dmytro Khyluk, Andzej Gzella, Krzysztof Bielawski, Anna Bielawska, Petr Dzubak, Sona Gurska, Marian Hajduch, Rostyslav Stoika, Roman Lesyk. Eur J Med Chem. 2023 Apr 5;252:115304.
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Ovarian cancer pathology characteristics as predictors of variant pathogenicity in BRCA1 and BRCA2. Denise G O'Mahony, Susan J Ramus, Melissa C Southey, Nicola S Meagher, Andreas Hadjisavvas, Esther M John, Ute Hamann, Evgeny N Imyanitov, Irene L Andrulis, Priyanka Sharma, Mary B Daly, Christopher R Hake, Jeffrey N Weitzel, Anna Jakubowska, Andrew K Godwin, Adalgeir Arason, Anita Bane, Jacques Simard, Penny Soucy, Maria A Caligo, Phuong L Mai, Kathleen B M Claes, Manuel R Teixeira, Wendy K Chung, Conxi Lazaro, Peter J Hulick, Amanda E Toland, Inge Sokilde Pedersen; HEBON Investigators; Susan L Neuhausen, Ana Vega, Miguel de la Hoya, Heli Nevanlinna, Mallika Dhawan, Valentina Zampiga, Rita Danesi, Liliana Varesco, Viviana Gismondi, Valerio Gaetano Vellone, Paul A James, Ramunas Janavicius, Liene Nikitina-Zake, Finn Cilius Nielsen, Thomas van Overeem Hansen, Tanja Pejovic, Ake Borg, Johanna Rantala, Kenneth Offit, Marco Montagna, Katherine L Nathanson, Susan M Domchek, Ana Osorio, María J García, Beth Y Karlan; GEMO Study Collaborators; Anna De Fazio, David Bowtell; AOCS Group; Lesley McGuffog, Goska Leslie, Michael T Parsons, Thilo Dörk, Lisa-Marie Speith, Elizabeth Santana Dos Santos, Alexandre André B A da Costa, Paolo Radice, Paolo Peterlongo, Laura Papi, Christoph Engel, Eric Hahnen, Rita K Schmutzler, Barbara Wappenschmidt, Douglas F Easton, Marc Tischkowitz, Christian F Singer, Yen Yen Tan, Alice S Whittemore, Weiva Sieh, James D Brenton, Drakoulis Yannoukakos, Florentia Fostira, Irene Konstantopoulou, Jana Soukupova, Michal Vocka; CZECANCA Consortium; Georgia Chenevix-Trench, Paul D P Pharoah, Antonis C Antoniou, David E Goldgar, Amanda B Spurdle, Kyriaki Michailidou; Consortium of Investigators of Modifiers of BRCA1/2; Evidence-based Network for the Interpretation of Germline Mutant Alleles Consortium. Br J Cancer. 2023 Apr 19. Online ahead of print.
doi: 10.1038/s41416-023-02263-5. PMID: 37076566
Personal comorbidities and their subsequent risks for liver, gallbladder and bile duct cancers. Kari Jussi Hemminki, Kristina Sundquist, Jan Sundquist, Asta Försti, Václav Liška, Akseli Hemminki, Xinjun Li. International Journal of Cancer 2023 Mar 15;152(6):1107-1114.
doi: 10.1002/ijc.34308. PMID: 36196489
Perspectives in the Application of High, Medium, and Low Molecular Weight Oat β-d-Glucans in Dietary Nutrition and Food Technology—A Short Overview. Leonid Sushytskyi, Andriy Synytsya, Jana Čopíková, Pavol Lukáč, Lenka Rajsiglová, Paolo Tenti, and Luca E. Vannucci. Foods 2023, 12, no. 6: 1121.
doi: 10.3390/foods12061121. PMID: 36981048; PMCID: PMC10048208
Phosphorylation of TRF2 promotes its interaction with TIN2 and regulates DNA damage response at telomeres. Radka Storchova, Matous Palek, Natalie Palkova, Pavel Veverka, Tomas Brom, Ctirad Hofr, Libor Macurek. Nucleic Acids Research. 2023; 51(3):1154-1172.
doi: 10.1093/nar/gkac1269. PMID: 36651296
PPM1D activity promotes the replication stress caused by cyclin E1 overexpression. Andra S. Martinikova, Miroslav Stoyanov, Anna Oravetzova, Yannik Kok, Sonbin Yu, Jana Dobrovolna, Pavel Janscak, Marcel van Vugt, Libor Macurek. Molecular Oncology. 2023 (E-pub ahead of print)
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Recent Advances in Methods for Circulating Tumor Cell Detection. Monika Vidlářová, Alona Řehulková, Pavel Stejskal, Andrea Prokopova, Hanus Slavik. Marián Hajdúch, Josef Srovnal. Int J Mol Sci. 2023 Feb 15;24(4):3902.
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Selectivity of Hydroxamate- and Difluoromethyloxadiazole-Based Inhibitors of Histone Deacetylase 6 In Vitro and in Cells. Jakub Ptacek, Ivan Snajdr, Jiri Schimer, Zsofia Kutil, Jana Mikesova, Petra Baranova, Barbora Havlinova, Werner Tueckmantel, Pavel Majer, Alan Kozikowski, Cyril Barinka. Int. J. Mol. Sci. 2023, 24, 4720.
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The emerging role of microtubules in invasion plasticity. Anna Legátová, Markéta Pelantová, Daniel Rösel, Jan Brábek, Aneta Škarková. Front Oncol. 2023 Feb 13;13:1118171.
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The KMT2A recombinome of acute leukemias in 2023. C Meyer, P Larghero, B Almeida Lopes, T Burmeister, D Gröger, R Sutton, N C Venn, G Cazzaniga, L Corral Abascal, G Tsaur, L Fechina, M Emerenciano, M S Pombo-de-Oliveira, T Lund-Aho, T Lundán, M Montonen, V Juvonen, J Zuna, J Trka, P Ballerini, H Lapillonne, V H J Van der Velden, E Sonneveld, E Delabesse, R R C de Matos, M L M Silva, S Bomken, K Katsibardi, M Keernik, N Grardel, J Mason, R Price, J Kim, C Eckert, L Lo Nigro, C Bueno, P Menendez, U Zur Stadt, P Gameiro, L Sedék, T Szczepański, A Bidet, V Marcu, K Shichrur, S Izraeli, H O Madsen, B W Schäfer, S Kubetzko, R Kim, E Clappier, H Trautmann, M Brüggemann, P Archer, J Hancock, J Alten, A Möricke, M Stanulla, J Lentes, A K Bergmann, S Strehl, S Köhrer, K Nebral, M N Dworzak, O A Haas, C Arfeuille, A Caye-Eude, H Cavé, R Marschalek. Leukemia. 2023 May;37(5):988-1005.
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Therapeutic Potential and Limitations of Curcumin as Antimetastatic Agent. Petr Dytrych, Zdeněk Kejík, Jan Hajduch, Robert Kaplánek, Kateřina Veselá, Kateřina Kučnirová, Markéta Skaličková, Anna Venhauerová, David Hoskovec, Pavel Martásek, Milan Jakubek. Biomedicine and Pharmacotherapy 2023,163, 114758.
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Triazole-based estradiol dimers prepared via CuAAC from 17α-ethinyl estradiol with five-atom linkers causing G2/M arrest and tubulin inhibition. Michal Jurášek, Jiří Řehulka, Lenka Hrubá, Aleksandra Ivanová, Soňa Gurská, Olena Mokshna, Pavel Trousil, Lukáš Huml, Pavel Polischchuk Marián Hajdúch, Pavel B Drašar, Petr Džubák. Bioorg Chem. 2023 Feb; 131:106334.
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Tunable Multivalent Platform for Immune Recruitment to Lower Antigen Expressing Cancers. Benjamin P M Lake, Ryan G Wylie, Cyril Bařinka, Anthony F Rullo. Angew Chem Int Ed Engl 2023, 62(9).
doi: 10.1002/anie.202214659. PMID: 36577087
Developmental changes in iron metabolism and erythropoiesis in mice with human gain-of-function erythropoietin receptor. Barbora Kralova, Lucie Sochorcova, Jihyun Song, Ondrej Jahoda, Katarina Hlusickova Kapralova, Josef T Prchal, Vladimir Divoky, Monika Horvathova. Am J Hematol. 2022 Oct;97(10):1286-1299.
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Thiosemicarbazones Can Act Synergistically with Anthracyclines to Downregulate CHEK1 Expression and Induce DNA Damage in Cell Lines Derived from Pediatric Solid Tumors. Silvia Paukovčeková, Maria Krchniakova, Petr Chlapek, Jakub Neradil, Jan Škoda, Renata Veselská. Int J Mol Sci 2022 Aug 1;23(15):8549.
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Fully automated virtual screening pipeline of FDA-approved drugs using Caver Web. Miloš Musil, Andrej Ježík, Marie Jankůjová, Jan Štourač, Jakub Galgonek, Saltuk Mustafa Eyrilmez, Jiří Vondrášek, Jiří Damborský, David Bednář. Comput Struct Biotechnol J. 2022, Nov 17;20:6512-6518.
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Current methods for studying metastatic potential of tumor cells. Pavla Bouchalová, Pavel Bouchal. Cancer Cell Int. 2022 Dec 9;22(1):394.
doi: 10.1186/s12935-022-02801-w. PMID: 36494720; PMCID: PMC9733110
The landscape of tumor cell states and spatial organization in H3-K27M mutant diffuse midline glioma across age and location. Ilon Liu, Li Jiang, Erik R Samuelsson, Sergio Marco Salas, Alexander Beck, Olivia A Hack, Daeun Jeong, McKenzie L Shaw, Bernhard Englinger, Jenna LaBelle, Hafsa M Mire, Sibylle Madlener, Lisa Mayr, Michael A Quezada, Maria Trissal, Eshini Panditharatna, Kati J Ernst, Jayne Vogelzang, Taylor A Gatesman, Matthew E Halbert, Hana Pálová, Petra Pokorná, Jaroslav Štěrba, Ondřej Slabý, Rene Geyeregger, Aaron Diaz, Izac J Findlay, Matthew D Dun, Adam Resnick, Mario L Suvà, David T W Jones, Sameer Agnihotri, Jessica Svedlund, Carl Koschmann, Christine Haberler, Thomas Czech, Irene Slavc, Jennifer A Cotter, Keith L Ligon, Sanda Alexandrescu, W K Alfred Yung, Isabel Arrillaga-Romany, Johannes Gojo, Michelle Monje, Mats Nilsson, Mariella G Filbin. Nat Genet. 2022 Dec;54(12):1881-1894.
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Electrochemical DNA biosensor coupled to LAMP reaction for early diagnostics of cervical precancerous lesions. Ravery Sebuyoya, Ludmila Moráňová, Nasim Izadi, Roman Hrstka, Milan Anton, Martin Bartošík. Biosensors and Bioelectronics: X Volume 12, December 2022, 100224.
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Electrochemical biosensors for analysis of DNA point mutations in cancer research. Kateřina Ondrášková, Ravery Sebuyoya, Ludmila Moráňová, Jitka Holčáková, Petr Voňka, Roman Hrstka, Martin Bartošík. Anal Bioanal Chem. 2023, Mar;415(6):1065-1085.
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Modulating the pharmacokinetic profile of Actinium-225-labeled macropa-derived radioconjugates by dual targeting of PSMA and albumin. Falco Reissig, Kristof Zarschler, Zbyněk Nový, Miloš Petřík, Kateřina Bendová, Daniela Kurfürstová, Jan Bouchal, Marie Charlotte Ludik, Florian Brandt, Klaus Kopka, Marta Khoylou, Hans-Jürgen Pietzsch, Marián Hajdúch, Constantin Mamat. Theranostics 2022, Oct 17;12(17):7203-7215.
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Characterization of drug effects on cell cultures from phase-contrast microscopy images. Denis Baručić, Sumit Kaushik, Jan Kybic, Jarmila Stanková, Petr Džubák, Marián Hajdúch.
Comput Biol Med 2022, Dec;151(Pt A):106171
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Chronic inflammation decreases HSC fitness by activating the druggable Jak/Stat3 signaling pathway. Srđan Grušanović, Petr Daněk, Maria Kuzmina, Miroslava Kari Adamcová, Burócziová, Monika, Romana Mikyšková, Karolina Vaníčková, Slađana Kosanović, Jana Pokorná, Milan Reiniš, Tomáš Brdička, Meritxell Alberich Jordà. EMBO Rep. 2023, Jan 9;24(1):e54729.
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γ-Tubulin in microtubule nucleation and beyond. Vadym Sulimenko, Eduarda Dráberová, Pavel Dráber. Front Cell Dev Biol. 2022, Sep 1;10:880761.
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Discovery of small molecule mechanistic target of rapamycin inhibitors as anti-aging and anti-cancer therapeutics. Žofia Chrienová, David Ryšánek, Patrik Olekšák, Dorota Starý, Marek Bajda, Milan Reiniš, Romana Mikyšková, Ondřej Novotný, Rudolf Andrýs, Adam Skarka, Pavla Vašicová, Josef Novák, Martin Vališ, Kamil Kuča, Zdeněk Hodný, Eugenie Nepovimová. Front Aging Neurosci. 2022 Dec 6;14:1048260.
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Involvement of Small Non-Coding RNA and Cell Antigens in Pathogenesis of Extramedullary Multiple Myeloma. Monika Vlachová, Jana Gregorová, Petra Vychytilová-Faltejsková, Natalia Anna Gabło, Lenka Radová, Lenka Pospíšilová, Martina Almáši, Martin Štork, Zdenka Knechtová, Jiří Minařík, Tereza Popková, Tomáš Jelínek, Roman Hájek, Luděk Pour, Lucie Říhová, Sabina Ševčíková. Int J Mol Sci. 2022, Nov 25;23(23):14765.
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Unexpected Heterogeneity of Newly Diagnosed Multiple Myeloma Patients with Plasmacytomas. Martin Štork, Sabina Ševčíková, Tomáš Jelínek, Jiří Minařík, Jakub Radocha, Tomáš Pika, Lenka Pospíšilová, Ivan Špička, Jan Štraub, Petr Pavlíček, Alexandra Jungová, Zdeňka Knechtová, Viera Sandecká, Vladimír Maisnar, Roman Hájek, Luděk Pour.
Biomedicines 2022, 10(10), 2535.
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More Than 2% of Circulating Tumor Plasma Cells Defines Plasma Cell Leukemia–Like Multiple Myeloma. Tomáš Jelínek, Renata Bezděková, David Žihala, Tereza Ševčíková, Anjana Anilkumar Sithara, Lenka Pospíšlová, Sabina Ševčíková, Petra Poláčková, Martin Štork, Zdeňka Knechtová, Ondřej Venglář, Veronika Kapustová, Tereza Popková, Ludmila Muroňová, Zuzana Chyra, Matouš Hrdinka, Michal Šimíček, Juan-Jose Garcés, Noemi Puig, Maria-Teresa Cedena, Artur Jurczyszyn, Jorge J Castillo, Miroslav Penka, Jakub Radocha, María Victoria Mateos, Jesús San Miguel, Bruno Paiva, Luděk Pour, Lucie Říhová, Roman Hájek. J Clin Oncol. 2022, Oct 31;JCO2201226.
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Distinct p53 phosphorylation patterns in chroniclymphocytic leukemia patients are reflected in theactivation of circumjacent pathways upon DNA damage. Veronika Mančíková, Michaela Pešová, Šárka Pavlová, Robert Helma, Kristýna Zavácká, Václav Hejret, Petr Taus, Jakub Hynšt, Karla Plevová, Jitka Malčíková, Šarka Pospíšilová. Mol. Oncol. 2023, Jan;17(1):82-97.
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Thiosemicarbazones and selected tyrosine kinase inhibitors synergize in pediatric solid tumors: NDRG1 upregulation and impaired prosurvival signaling in neuroblastoma cells. Maria Krchniakova, Silvia Paukovčeková, Petr Chlapek, Jakub Neradil, Jan Škoda, Renata Veselská. Front Pharmacol. 2022 Sep 7;13:976955.
doi: 10.3389/fphar.2022.976955. PMID: 36160437; PMCID: PMC9490180
Disulfriam increases the efficiency of 5-fluorouracil in organotypic cultures of colorectal carcinoma. Michal Hendrych, Kamila Říhová, Barbora Adamová, Vojtěch Hradil, Marek Stiborek, Petr Vlček, Markéta Hermanová, Jana Vašíčková, Petr Beneš, Jan Šmarda, Viktor Kanický, Jan Preisler, Jarmila Navrátilová. Biomed Pharmacother 2022, Sep;153:113465.
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SoluProtMutDB: A manually curated database of protein solubility changes upon mutations. Jan Velecký, Marie Hamšíková, Jan Šťourač, Miloš Musil, Jiří Damborský, David Bednář, Stanislav Mazurenko. Comput Struct Biotechnol J. 2022, Nov 9;20:6339-6347.
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Minimal residual disease in BCR: ABL1-positive acute lymphoblastic leukemia: different significance in typical ALL and in CML-like disease. Jan Zuna, Lenka Hovorková, Justina Krotká, Amelie Koehrmann, Michela Bardini, Lucie Winkowská, Eva Froňková, Julia Alten, Rolf Koehler, Cornelia Eckert, Lisa Brizzolara, Marie Trková, Jan Stuchlý, Martin Zimmermann, Paola De Lorenzo, Maria Grazia Valsecchi, Valentino Conter, Jan Starý, Martin Schrappe, Andrea Biondi, Jan Trka, Markéta Žaliová, Giovanni Cazzaniga, Gunnar Cario.
Leukemia volume 36, pages 2793–2801 (2022).
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Long Non-Coding RNA and microRNA Interplay in Colorectal Cancer and Their Effect on the Tumor Microenvironment. Marie Rajtmajerová, Andriy Trailin, Václav Liška, Kari Jussi Hemminki, Filip Ambrozkiewicz. Cancers 2022, 14(21), 5450.
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Activated Hepatic Stellate Cells in Hepatocellular Carcinoma: Their Role as a Potential Target for Future Therapies. Esraa Ali, Andriy Trailin, Filip Ambrozkiewicz, Václav Liška, Kari Jussi Hemminki. Int. J. Mol. Sci. 2022, 23(23), 15292.
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LACTB exerts tumor suppressor properties in ovarian cancer through regulation of Slug. Valentina Cutano, Jessica Marianne Ferreira Mendes, Sara Escudeiro-Lopes, Susana Machado, Judith Vinaixa Forner, Juan M Gonzales-Morena, Martin Převorovský, Viacheslav Zemlianski, Yuxiong Feng, Petra Králová Viziová, Andrea Hartmanová, Beáta Malčeková, Pavel Jakoubě, Sonia Iyer, Zuzana Kečkéšová. Life Sci Alliance. 2022 Nov 14;6(1):e202201510.
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TROP2 Represents a Negative Prognostic Factor in Colorectal Adenocarcinoma and Its Expression Is Associated with Features of Epithelial–Mesenchymal Transition and Invasiveness. Jiří Švec, Monika Šťastná, Lucie Janečková, Dušan Hrčkulák, Martina Vojtěchová, Jakub Onhajzer, Vítězslav Kříž, Kateřina Galušková, Eva Šloncová, Jan Kubovčiak, Lucie Pfeiferová, Jan Hrudka, Radoslav Matěj, Petr Waldauf, Lukáš Havlůj, Michal Kolář, Vladimír Kořínek. Cancers (Basel) 2022, Aug 26;14(17):4137.
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FBXO38 Ubiquitin Ligase Controls Centromere Integrity via ZXDA/B Stability. Nikol Dibus, Vladimír Kořínek, Lukáš Čermák. Front Cell Dev Biol. 2022 Jun 23;10:929288.
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NGS better discriminates true MRD positivity for the risk stratification of childhood ALL treated on MRD-based protocol. Michael Svatoň, Aneta Skotnicová, Leona Řezníčková, Andrea Rennerová, Taťána Valová, Michaela Kotrová, Vincent H J van der Velden, Monika Brüggemann, Nikos Darzentas, Anton W Langerak, Jan Zuna, Jan Starý, Jan Trka, Eva Froňková. Blood (2023) 141 (5): 529–533.
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Azulene hydrazide-hydrazones for selective targeting of pancreatic cancer cells. Tereza Brogyányi, Robert Kaplánek, Zdeněk Kejík, Božena Hosnedlová, Veronika Antonyová, Nikita Abramenko, Kateřina Veselá, Pavel Martásek, Martin Vokurka, Des R Richardson, Milan Jakubek. Biomedicine & Pharmacotherapy, 2022 Nov; 155:113736.
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Restored biosynthetic pathways induced by MSCs serve as rescue mechanism in leukemia cells after L-asparaginase therapy. Natividad Alquezar-Artieda, Daniela Kužílková, Jennie Roberts, Katerina Hložková, Alena Pecinová, Petr Pecina, Martina Zwyrtková, Eliška Potůčková, Daniel Kavan, Ivana Hermanová, Markéta Žaliová, Petr Novák, Tomáš Mráček, Lucie Šrámková, Daniel A Tennant, Jan Trka, Júlia Starková. Blood Adv. 2022 Nov 18;bloodadvances.2021006431.
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Pentamethinium salts suppress key metastatic processes by regulating mitochondrial function and inhibiting dihydroorotate dehydrogenase respiration. Jindriška Leischner Fialová, Kateřina Hönigová, Martina Raudenská, Lucie Mikšátková, Renata Zobalová, Jiří Navrátil, Jana Šmigová, Taraka Ramji Moturu, Tomáš Vicar, Jan Balvan, Kateřina Veselá, Nikita Abramenko, Zdeněk Kejík, Robert Kaplánek, Jaromír Gumulec, Daniel Rosel, Pavel Martásek, Jan Brábek. Jiří Neužil, Michal Masařík. Biomedicine & Pharmacotherapy, 2022 Oct; 154:113582.
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Complex genetic and histopathological study of 15 patient-derived xenografts of aggressive lymphomas. Radek Jakša, Jana Karolová, Michael Svatoň, Dmitry Kazantsev, Martina Grajciarová, Eva Pokorná, Zbyněk Tonar, Magdalena Klánová, Lucie Winkowska, Diana Maláriková, Petra Vočková, Kristina Forsterová, Nicol Renešová, Alexandra Dolníková, Kristýna Nožičková, Pavel Dundr, Eva Froňková, Marek Trněný, Pavel Klener. Laboratory Investigation, 2022 Sep; 102(9):957-965.
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Non-Psychotropic Cannabinoids as Inhibitors of TET1 Protein. Veronika Antonyová, Zdeněk Kejík, Tereza Brogyanyi, Robert Kaplánek, Kateřina Veselá, Nikita Abramenko, Tomáš Ocelka, Michal Masařík, Adam Matkowski, Jakub Gburek, Renata Abel, Andrean Goede, Robert Preissner, Petr Novotný, Milan Jakubek. Bioorganic Chemistry, 2022 Jul; 124:105793.
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Targeting of the Mitochondrial TET1 Protein by Pyrrolo[3,2-b]pyrrole Chelators. Veronika Antonyová, Ameneh Tatar, Tereza Brogyányi, Zdeněk Kejík, Robert Kaplánek, Fréderic Vellieux, Nikita Abramenko, Alla Sinica, Jan Hajduch, Petr Novotný, Bettie Sue Masters, Pavel Martásek, Milan Jakubek. Int. J. Mol. Sci, 2022 Sep; 16;23(18):10850.
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G-CSF plus azacitidine versus azacitidine alone for patients with high-risk myelodysplastic syndrome: academic, open label, randomized trial. Tomáš Stopka, Lubomír Minařík, Nina Dusílková, Michal Pešta, Vojtěch Kulvait, Martin Špaček, Zuzana Zemanová, Marta Kalousová, Anna Jonášová. Blood Cancer Journal, volume 12, article number: 105 (2022).
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Combined Approach to Leukemic Differentiation Using Transcription Factor PU.1-Enhancing Agents. Petra Bašová, Helena Paszeková, Lubomír Minařík, Martina Dluhošová, Pavel Burda, Tomáš Stopka. Int. J. Mol. Sci, 2022, Jun; 16;23(12):6729.
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Quaternized Chitosan/Heparin Polyelectrolyte Multilayer Films for Protein Delivery. Tomasz Urbaniak, Gabriela S. García-Briones, Alexander Zhigunov, Sviatoslav Hladysh, Edyta Adrian, Volodymyr Lobaz, Tereza Krunclová, Olga Janoušková, Ognen Pop-Georgievski, Dana Kubies. Biomacromolecules 2022, 23, 11, 4734–4748.
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New-Generation Heterocyclic Bis-Pentamethinium Salts as Potential Cytostatic Drugs with Dual IL-6R and Mitochondria-Targeting Activity. Veronika Talianová, Zdeněk Kejík, Robert Kaplánek, Kateřina Veselá, Nikita Abramenko, Lukáš Lacina, Karolína Strnadová, Barbora Dvořánková, Pavel Martásek, Michal Masařík, Magdalena Houdová Megová, Petr Bušek, Jana Křížová, Lucie Zdražilová, Hana Hansíková, Erik Vlčák, Vlada Filimonenko, Aleksi Šedo, Karel Smetana Jr, Milan Jakubek. Pharmaceutics 2022, 14(8), 1712.
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Biomarker Dynamics and Long-Term Treatment Outcomes in Breast Cancer Patients with Residual Cancer Burden after Neoadjuvant Therapy. Milos Holanek, Iveta Selingerova, Pavel Fabian, Oldrich Coufal, Ondrej Zapletal, Katarina Petrakova, Tomas Kazda, Roman Hrstka, Alexandr Poprach, Maria Zvarikova, Ondrej Bilek, Marek Svoboda. Diagnostics 2022, 12(7), 1740.
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Design, Synthesis, and Biochemical and Biological Evaluation of Novel 7-Deazapurine Cyclic Dinucleotide Analogues as STING Receptor Agonists. Zdeněk Vavřina, Pavla Perlíková, Nemanja Milisavljević, Florian Chevrier, Miroslav Smola, Joshua Smith, Milan Dejmek, Vojtěch Havlíček, Miloš Buděšínský, Radek Liboska, Lenka Vaneková, Jiří Brynda, Evzen Boura, Pavlína Řezáčová, Michal Hocek, and Gabriel Birkuš. J. Med. Chem.2022, 65, 20, 14082–14103.
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Emetine blocks DNA replication via proteosynthesis inhibition not by targeting Okazaki fragments. David Lukac, Zuzana Machacova, Pavel Moudry. Life Sci Alliance. 2022 Sep 9;5(12):e202201560.
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Synthesis of Polycyclic Hetero-Fused 7-Deazapurine Heterocycles and Nucleosides through C-H Dibenzothiophenation and Negishi Coupling. Chao Yang, Lenka Poštová Slavětínská, Marianne Fleuti, Blanka Klepetářová, Michal Tichý, Soňa Gurská, Petr Pavliš, Petr Džubák, Marián Hajdúch, Michal Hocek. J. Am. Chem. Soc. 2022, 144, 42, 19437–19446.
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Preparation, In Vitro Affinity, and In Vivo Biodistribution of Receptor-Specific Ga-Labeled Peptides Targeting Vascular Endothelial Growth Factor Receptors. Pavel Barta, Rajamanikkam Kamaraj, Monika Kucharova, Zbynek Novy, Milos Petrik, Katerina Bendova, Marian Hajduch, Petr Pavek, Frantisek Trejtnar. Bioconjugate Chem. 2022, 33, 10, 1825–1836.
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Modulation of FLT3-ITD and CDK9 in acute myeloid leukaemia cells by novel proteolysis targeting chimera (PROTAC). Eva Řezníčková, Soňa Krajčovičová, Miroslav Peřina, Markéta Kovalová, Miroslav Soural, Vladimír Kryštof. Europen Journal of Medicinal Chem. 2022, 243, 114792.
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Triterpenoid pyrazines and pyridines – Synthesis, cytotoxicity, mechanism of action, preparation of prodrugs. Jiří Hodoň, Ivo Frydrych, Zdeňka Trhlíková, Jan Pokorný, Lucie Borková, Sandra Benická, Martin Vlk, Barbora Lišková, Agáta Kubíčková, Martina Medvedíková, Martin Pisár, Jan Šarek, Viswanath Das, Anna Ligasová, Karel Koberna, Petr Džubák, Marián Hajdúch, Milan Urban. Europen Journal of Medicinal Chem. 2022, 243,114777.
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Mixture Effects of Tryptophan Intestinal Microbial Metabolites on Aryl Hydrocarbon Receptor Activity Aneta Vrzalová, Petra Pečinková, Peter Illés, Soňa Gurská, Petr Džubák, Martin Szotkowski, Marián Hajdúch, Sridhar Mani, Zdeněk Dvořák.
Int. J. Mol. Sci. 2022, 23 (18), 10825.
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