As part of the News in Biomedical Research lecture series, Lindsay Case from Massachusetts Institute of Technology visited the Institute of Biochemistry and Experimental Oncology at the First Faculty of Medicine, Charles University. The lecture by the leading American scientist was held at the invitation of Martin Sztacho, whose research group is part of the NUVR, and attracted nearly 50 students, postdoctoral fellows, and researchers.
In her lecture entitled “Phase Separation Regulates Cell Adhesion and Kinase Signaling,” Dr. Case focused on the role of phase separation in the organization of dynamic cellular structures and the regulation of signaling processes. She demonstrated how this mechanism contributes to the formation of integrin adhesion complexes and can directly influence the activation of signaling pathways through kinase autophosphorylation. The audience also gained an up-to-date perspective on the spatial organization of cellular signaling and its importance for modern biomedical research.
“We greatly appreciate the opportunity to continue our scientific collaboration with Lindsay Case’s team. Her visit opened up further opportunities for joint research in the fields of cell signaling and phase separation,” said Martin Sztacho. The lecture also highlighted the importance of international collaboration and the sharing of current scientific knowledge for the further advancement of oncology research.
